Tel:

Email:

EN
Cat. No. Size / Unit Price Qty
CS-W001157 4
Total: USD 88.00

3-Fluorocyclobutanecarboxylic acid

  • CAS No. 122665-96-7

  • Cat. No. CS-0036337
  • Purity≥97%
  • MDL No.MFCD09834117
  • HazMat Fee +

    HazMat Fee

    An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it. There is a HazMat shipping fee for each item that qualifies as a dangerous good, except in the following scenarios:

    The shipment is processed through FedEx Ground under the Limited Quantity option.

    Each bottle is packed as an Excepted Quantity, with a maximum of 1g for items in class 6.1 packing group I or II, and up to 25g for all other hazardous materials.

    If shipping is charged to your FedEx account, the HazMat fee will be billed directly by the courier. Otherwise, the fee will be included on your invoice. To help you avoid the HazMat fee, we can package a 5g order of a class 6.1 packing group I or II material as five separate 1g units, and a 100g order of any other dangerous good as four 25g units. This packaging adjustment will be made unless you instruct otherwise on your purchase order. Below, you will find the fee schedule from FedEx for handling hazardous materials.

    Type
    HazMat Fee
    Excepted Quantity $0.00
    FedEx Limited Quantities Ground $0.00
    Hazmat Ground shipping $50.00+
    Inaccessible (Haz class 6.1 or 9), Domestic $68.00+
    Accessible (Haz class 3, 4, 5 or 8), Domestic $158.00+
    Inaccessible (Haz class 6.1 or 9), International $108.00+
    Accessible (Haz class 3, 4, 5 or 8), International $238.00+

    An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it.

    There is a HazMat shipping fee for each item that qualifies as a dangerous good. Please contact our quotation team via email to confirm the details.

*For research and further manufacturing use only, not for direct human use.

3-Fluorocyclobutanecarboxylic acid|CS-0036337

Structure of 122665-96-7

Please choose your location and provide accurate information for you
Size Stock
Price Quantity

* Please select Quantity before adding items.

Description

3-Fluorocyclobutanecarboxylic acid features a strained cyclobutane ring with a fluorine atom at the 3-position, enhancing its metabolic stability and electronic properties. This configuration imparts unique conformational rigidity, enabling precise spatial control in medicinal chemistry applications. The carboxylic acid group facilitates direct derivatization or salt formation for improved solubility and handling.

Application

3-Fluorocyclobutanecarboxylic acid serves as a valuable building block in medicinal chemistry, offering a rigid, bioisosteric replacement for cyclopropyl or cyclohexyl moieties. Its fluorinated cyclobutane core enhances metabolic stability and modulates lipophilicity, while the carboxylic acid functionality enables direct derivatization via amide formation, esterification, or coupling reactions. The compound exhibits good bench stability and is compatible with standard purification methods, facilitating integration into diverse synthetic sequences for targeted scaffold development.

General Information

  • CAS No. 122665-96-7
  • Cat. No. CS-0036337
  • Purity ≥97%
  • MDL No. MFCD09834117
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₅H₇FO₂
  • Molecular Weight 118.11
  • Synonym(s) cyclobutanecarboxylic acid, 3-fluoro-
  • SMILES C1C(CC1F)C(=O)O

Computational Chemistry Data

  • TPSA   37.3
  • LogP   0.8191
  • H_Acceptors   1
  • H_Donors   1
  • Rotatable_Bonds   1

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302
Precautionary Statements : P264-P270-P330-P501

Quality Control

To search for quality control of cas , please enter both the product number and the lot/batch number.

Other Classifications

Recently Viewed Products

Leave US a Message
Upload Pictures

Key Words

  • 3-Fluorocyclobutanecarboxylic acid sigma3-Fluorocyclobutanecarboxylic acid manufacturer3-Fluorocyclobutanecarboxylic acid price3-Fluorocyclobutanecarboxylic acid structure3-Fluorocyclobutanecarboxylic acid SDSbuy 3-Fluorocyclobutanecarboxylic acid3-Fluorocyclobutanecarboxylic acid supplier3-Fluorocyclobutanecarboxylic acid uses3-Fluorocyclobutanecarboxylic acid molecular weightprice of 3-Fluorocyclobutanecarboxylic acid3-Fluorocyclobutanecarboxylic acid chemical name formula of 3-Fluorocyclobutanecarboxylic acid
This product is not sold in the region.
Confirm
How to get a Lot Number

Lot numbers can be found on the outside label of a product:

ChemScene Label