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2-(4-Methyl-2-oxo-1,2-dihydropyridin-1-yl)acetic acid

  • CAS No. 122180-16-9

  • Cat. No. CS-0214619
  • Purity≥98%
  • MDL No.None

*For research and further manufacturing use only, not for direct human use.

2-(4-Methyl-2-oxo-1,2-dihydropyridin-1-yl)acetic acid|CS-0214619

Structure of 122180-16-9

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General Information

  • CAS No. 122180-16-9
  • Cat. No. CS-0214619
  • Purity ≥98%
  • MDL No. None
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₈H₉NO₃
  • Molecular Weight 167.16
  • Synonym(s) (4-Methyl-2-oxo-2H-pyridin-1-yl)-acetic acid
  • SMILES CC1=CC(=O)N(C=C1)CC(=O)O

Description

This pyridine-based carboxylic acid integrates a methyl-substituted 1,2-dihydropyridinone scaffold with a reactive acetic acid handle. The electron-deficient dihydropyridinone ring enables efficient coupling reactions, while the pendant carboxylate offers convenient derivatization. Bench-stable and moisture-tolerant, this reagent streamlines access to functionalized heterocycles in synthetic and medicinal chemistry workflows.

Application

2-(4-Methyl-2-oxo-1,2-dihydropyridin-1-yl)acetic acid serves as a versatile building block for heterocyclic synthesis, enabling efficient access to pyridone-derived scaffolds. Its carboxylic acid functionality facilitates derivatization and conjugation, while the dihydropyridinone core exhibits stability under standard bench conditions. The molecule functions effectively in coupling reactions and provides a platform for constructing biologically relevant frameworks through established synthetic protocols.

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501

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Computational Chemistry Data

  • TPSA   59.3
  • LogP   0.24132
  • H_Acceptors   3
  • H_Donors   1
  • Rotatable_Bonds   2

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