Tel:

Email:

EN
Cat. No. Size / Unit Price Qty
CS-W001157 4
Total: USD 88.00

N-[3,5-Bis(trifluoromethyl)phenyl]-N'-[(1S,2S)-2-(dimethylamino)cyclohexyl]urea

  • CAS No. 1221442-12-1

  • Cat. No. CS-0092949
  • Molecule weight397.36
  • Purity≥97%
  • MDL No.None

*For research and further manufacturing use only, not for direct human use.

N-[3,5-Bis(trifluoromethyl)phenyl]-N'-[(1S,2S)-2-(dimethylamino)cyclohexyl]urea|CS-0092949

Structure of 1221442-12-1

Please choose your location and provide accurate information for you
Size Stock
Price Quantity

* Please select Quantity before adding items.

General Information

  • CAS No. 1221442-12-1
  • Cat. No. CS-0092949
  • Purity ≥97%
  • MDL No. None
  • Storage 4°C, protect from light, stored under nitrogen
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₇H₂₁F₆N₃O
  • Molecular Weight 397.36
  • Synonym(s) N-[3,5-bis(trifluoroMethyl)phenyl]-N'-[(1S,2S)-2-(diMethylaMino)cyclohexyl]-Urea
  • SMILES CN([C@H]1CCCC[C@@H]1NC(NC2=CC(C(F)(F)F)=CC(C(F)(F)F)=C2)=O)C

Description

This urea derivative features a sterically hindered cyclohexyl amine moiety paired with a highly electron-deficient trifluoromethylated aryl group, enabling strong hydrogen-bonding interactions and enhanced metabolic stability. The scaffold integrates robust solubility characteristics across diverse organic solvents and demonstrates excellent bench stability under ambient conditions.

Application

N-[3,5-Bis(trifluoromethyl)phenyl]-N'-[(1S,2S)-2-(dimethylamino)cyclohexyl]urea serves as a versatile building block in medicinal chemistry, enabling the construction of bioactive heterocycles through standard urea coupling protocols. The trifluoromethylated aryl group enhances metabolic stability and lipophilicity, while the chiral cyclohexylamine moiety provides stereochemical control in target-directed synthesis. Its bench-stable nature and compatibility with diverse reaction conditions facilitate efficient purification and scalability in API development workflows.

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P280-P302+P352

Quality Control

To search for quality control of cas , please enter both the product number and the lot/batch number.

Computational Chemistry Data

  • TPSA   44.37
  • LogP   4.7185
  • H_Acceptors   2
  • H_Donors   2
  • Rotatable_Bonds   3

Recently Viewed Products

Leave US a Message
Upload Pictures

Key Words

  • 1221442-12-1 sigma1221442-12-1 manufacturer1221442-12-1 price1221442-12-1 structure1221442-12-1 SDSbuy 1221442-12-11221442-12-1 supplier1221442-12-1 uses1221442-12-1 molecular weightprice of 1221442-12-11221442-12-1 chemical name formula of 1221442-12-1
This product is not sold in the region.
Confirm
How to get a Lot Number

Lot numbers can be found on the outside label of a product:

ChemScene Label