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Structure of 1221442-12-1
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This urea derivative features a sterically hindered cyclohexyl amine moiety paired with a highly electron-deficient trifluoromethylated aryl group, enabling strong hydrogen-bonding interactions and enhanced metabolic stability. The scaffold integrates robust solubility characteristics across diverse organic solvents and demonstrates excellent bench stability under ambient conditions.
N-[3,5-Bis(trifluoromethyl)phenyl]-N'-[(1S,2S)-2-(dimethylamino)cyclohexyl]urea serves as a versatile building block in medicinal chemistry, enabling the construction of bioactive heterocycles through standard urea coupling protocols. The trifluoromethylated aryl group enhances metabolic stability and lipophilicity, while the chiral cyclohexylamine moiety provides stereochemical control in target-directed synthesis. Its bench-stable nature and compatibility with diverse reaction conditions facilitate efficient purification and scalability in API development workflows.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P280-P302+P352
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Lot numbers can be found on the outside label of a product: