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Structure of 1218790-24-9
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tert-Butyl 6-chloro-3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-indole-1-carboxylate features a boronate ester group enabling reliable Suzuki-Miyaura coupling, paired with a chlorine substituent for orthogonal reactivity. This bench-stable, moisture-tolerant building block integrates efficiently into complex heterocycles and biaryl architectures under standard conditions.
tert-Butyl 6-chloro-3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-indole-1-carboxylate serves as a versatile boron-containing building block for palladium-catalyzed cross-coupling reactions. The 6-chloroindole moiety enables selective functionalization via Suzuki-Miyaura coupling, while the protected indole nitrogen and stable boronate group offer excellent bench stability and compatibility with diverse reaction conditions. This reagent facilitates efficient access to substituted indole scaffolds commonly found in medicinal chemistry and agrochemical research.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: