Methyl 2-(2-chloropyrimidin-4-yl)acetate

Name: Methyl 2-(2-chloropyrimidin-4-yl)acetate
Brand: ChemScene
Availability: InStock
Rating: 5 (1 reviews)

CAS No. 1216129-71-3
Cat. No. CS-0214712
Purity≥97%
MDL No.None

HazMat Fee +

HazMat Fee

An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it. There is a HazMat shipping fee for each item that qualifies as a dangerous good, except in the following scenarios:

The shipment is processed through FedEx Ground under the Limited Quantity option.

Each bottle is packed as an Excepted Quantity, with a maximum of 1g for items in class 6.1 packing group I or II, and up to 25g for all other hazardous materials.

If shipping is charged to your FedEx account, the HazMat fee will be billed directly by the courier. Otherwise, the fee will be included on your invoice. To help you avoid the HazMat fee, we can package a 5g order of a class 6.1 packing group I or II material as five separate 1g units, and a 100g order of any other dangerous good as four 25g units. This packaging adjustment will be made unless you instruct otherwise on your purchase order. Below, you will find the fee schedule from FedEx for handling hazardous materials.

Type	HazMat Fee
Excepted Quantity	$0.00
FedEx Limited Quantities Ground	$0.00
Hazmat Ground shipping	$50.00+
Inaccessible (Haz class 6.1 or 9), Domestic	$68.00+
Accessible (Haz class 3, 4, 5 or 8), Domestic	$158.00+
Inaccessible (Haz class 6.1 or 9), International	$108.00+
Accessible (Haz class 3, 4, 5 or 8), International	$238.00+

An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it.

There is a HazMat shipping fee for each item that qualifies as a dangerous good. Please contact our quotation team via email to confirm the details.

*For research and further manufacturing use only, not for direct human use.

Methyl 2-(2-chloropyrimidin-4-yl)acetate|CS-0214712

Structure of 1216129-71-3

Size

Price

Quantity

* Please select Quantity before adding items.

General Information

CAS No. 1216129-71-3
Cat. No. CS-0214712
Purity ≥97%
MDL No. None
Storage 4°C, sealed storage, away from moisture and light
Shipping Room temperature in continental US; may vary elsewhere.
Molecular Formula C₇H₇ClN₂O₂
Molecular Weight 186.60
Synonym(s) 4-Pyrimidineacetic acid, 2-chloro-, methyl ester
SMILES COC(=O)CC1=NC(=NC=C1)Cl

Description

Methyl 2-(2-chloropyrimidin-4-yl)acetate features a pyrimidine core functionalized with a chloro group at C2 and an acetyl ester side chain, enabling direct integration into pharmaceutical intermediates. The electron-deficient pyrimidine ring enhances reactivity in nucleophilic substitution cascades, while the methyl ester serves as a stable handle for subsequent transformations under standard conditions.

Application

Methyl 2-(2-chloropyrimidin-4-yl)acetate serves as a versatile building block in medicinal chemistry, enabling efficient access to pyrimidine-based scaffolds. The chloropyrimidine moiety facilitates nucleophilic substitution reactions, while the ester group supports subsequent transformations including hydrolysis, reduction, or coupling protocols. This compound exhibits good bench stability and is compatible with standard reaction conditions, making it well-suited for modular synthesis of bioactive heterocycles and API intermediates.

Safety Information

Download SDS

GHS Pictogram :	GHS No : GHS07
Signal Word : Warning	UN#: N/A
Class : N/A	Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362-P405-P501

Quality Control

To search for quality control of cas , please enter both the product number and the lot/batch number.

Computational Chemistry Data

TPSA 52.08
LogP 0.8455
H_Acceptors 4
H_Donors 0
Rotatable_Bonds 2

Other Classifications

Building Blocks Functional Group Ester

Building Blocks Skeleton Aromatic heterocycle compounds Pyrimidine compounds

Key Words

Methyl 2-(2-chloropyrimidin-4-yl)acetate sigmaMethyl 2-(2-chloropyrimidin-4-yl)acetate manufacturerMethyl 2-(2-chloropyrimidin-4-yl)acetate priceMethyl 2-(2-chloropyrimidin-4-yl)acetate structureMethyl 2-(2-chloropyrimidin-4-yl)acetate SDSbuy Methyl 2-(2-chloropyrimidin-4-yl)acetateMethyl 2-(2-chloropyrimidin-4-yl)acetate supplierMethyl 2-(2-chloropyrimidin-4-yl)acetate usesMethyl 2-(2-chloropyrimidin-4-yl)acetate molecular weightprice of Methyl 2-(2-chloropyrimidin-4-yl)acetateMethyl 2-(2-chloropyrimidin-4-yl)acetate chemical name formula of Methyl 2-(2-chloropyrimidin-4-yl)acetate

Salutation:	*Country or Region:
*Applicant Name:	*Organization Name:
*Email Address:	Quantity:
CAS NO. :	Product Name:
Remarks:
Upload Pictures

CAS.No.		Product Name
Applicant Name *		Email Address *
Phone Number *		Organization Name*
Country or Region*		Quantity*
Remarks:

Product Name:
Cat. No.: .		CAS NO. :
Quantity:

Methyl 2-(2-chloropyrimidin-4-yl)acetate

CAS No. 1216129-71-3

Recommended Products