3-Chloro-5-fluoropyridin-2(1H)-one

Name: 3-Chloro-5-fluoropyridin-2(1H)-one
Brand: ChemScene
Availability: InStock
Rating: 5 (1 reviews)

CAS No. 1214345-43-3
Cat. No. CS-0064676
Purity≥97%
MDL No.MFCD13185439

HazMat Fee +

HazMat Fee

An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it. There is a HazMat shipping fee for each item that qualifies as a dangerous good, except in the following scenarios:

The shipment is processed through FedEx Ground under the Limited Quantity option.

Each bottle is packed as an Excepted Quantity, with a maximum of 1g for items in class 6.1 packing group I or II, and up to 25g for all other hazardous materials.

If shipping is charged to your FedEx account, the HazMat fee will be billed directly by the courier. Otherwise, the fee will be included on your invoice. To help you avoid the HazMat fee, we can package a 5g order of a class 6.1 packing group I or II material as five separate 1g units, and a 100g order of any other dangerous good as four 25g units. This packaging adjustment will be made unless you instruct otherwise on your purchase order. Below, you will find the fee schedule from FedEx for handling hazardous materials.

Type	HazMat Fee
Excepted Quantity	$0.00
FedEx Limited Quantities Ground	$0.00
Hazmat Ground shipping	$50.00+
Inaccessible (Haz class 6.1 or 9), Domestic	$68.00+
Accessible (Haz class 3, 4, 5 or 8), Domestic	$158.00+
Inaccessible (Haz class 6.1 or 9), International	$108.00+
Accessible (Haz class 3, 4, 5 or 8), International	$238.00+

An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it.

There is a HazMat shipping fee for each item that qualifies as a dangerous good. Please contact our quotation team via email to confirm the details.

*For research and further manufacturing use only, not for direct human use.

3-Chloro-5-fluoropyridin-2(1H)-one|CS-0064676

Structure of 1214345-43-3

Size

Price

Quantity

* Please select Quantity before adding items.

General Information

CAS No. 1214345-43-3
Cat. No. CS-0064676
Purity ≥97%
MDL No. MFCD13185439
Storage Store at room temperature
Shipping Room temperature in continental US; may vary elsewhere.
Molecular Formula C₅H₃ClFNO
Molecular Weight 147.53
Synonym(s) 3-Chloro-5-fluoro-2-hydroxypyridine
SMILES O=C1C(Cl)=CC(F)=CN1

Description

3-Chloro-5-fluoropyridin-2(1H)-one features a fused heterocyclic core with orthogonal halogen substituents enabling precise functionalization. This bench-stable, moisture-tolerant scaffold integrates readily into synthetic routes for bioactive molecules, particularly in medicinal chemistry and agrochemical development.

Application

3-Chloro-5-fluoropyridin-2(1H)-one serves as a versatile building block in medicinal chemistry, enabling efficient access to fluorinated heterocyclic scaffolds. Its orthogonal reactivity allows selective functionalization at the C3 chlorine and C5 fluorine positions, facilitating Suzuki-Miyaura, Buchwald-Hartwig, and nucleophilic substitution reactions. The compound exhibits excellent bench stability and compatibility with common protecting group strategies, making it ideal for multi-step synthesis of API candidates and kinase inhibitor frameworks.

Safety Information

Download SDS

GHS Pictogram :	GHS No : GHS07
Signal Word : Warning	UN#: N/A
Class : N/A	Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P280-P302+P352

Quality Control

To search for quality control of cas , please enter both the product number and the lot/batch number.

Computational Chemistry Data

TPSA 32.86
LogP 1.1674
H_Acceptors 1
H_Donors 1
Rotatable_Bonds 0

Other Classifications

Building Blocks Functional Group Chloride

Building Blocks Skeleton Aromatic heterocycle compounds Pyridine compounds

Key Words

3-Chloro-5-fluoropyridin-2(1H)-one sigma3-Chloro-5-fluoropyridin-2(1H)-one manufacturer3-Chloro-5-fluoropyridin-2(1H)-one price3-Chloro-5-fluoropyridin-2(1H)-one structure3-Chloro-5-fluoropyridin-2(1H)-one SDSbuy 3-Chloro-5-fluoropyridin-2(1H)-one3-Chloro-5-fluoropyridin-2(1H)-one supplier3-Chloro-5-fluoropyridin-2(1H)-one uses3-Chloro-5-fluoropyridin-2(1H)-one molecular weightprice of 3-Chloro-5-fluoropyridin-2(1H)-one3-Chloro-5-fluoropyridin-2(1H)-one chemical name formula of 3-Chloro-5-fluoropyridin-2(1H)-one

Salutation:	*Country or Region:
*Applicant Name:	*Organization Name:
*Email Address:	Quantity:
CAS NO. :	Product Name:
Remarks:
Upload Pictures

CAS.No.		Product Name
Applicant Name *		Email Address *
Phone Number *		Organization Name*
Country or Region*		Quantity*
Remarks:

Product Name:
Cat. No.: .		CAS NO. :
Quantity:

3-Chloro-5-fluoropyridin-2(1H)-one

CAS No. 1214345-43-3

Recommended Products