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CS-W001157 4
Total: USD 88.00

4-Fluoro-2-difluoromethoxynitrobenzene

  • CAS No. 1214329-62-0

  • Cat. No. CS-W000041
  • Purity≥95%
  • MDL No.MFCD14698446

*For research and further manufacturing use only, not for direct human use.

4-Fluoro-2-difluoromethoxynitrobenzene|CS-W000041

Structure of 1214329-62-0

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General Information

  • CAS No. 1214329-62-0
  • Cat. No. CS-W000041
  • Purity ≥95%
  • MDL No. MFCD14698446
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₇H₄F₃NO₃
  • Molecular Weight 207.11
  • Synonym(s) 2-(Difluoromethoxy)-4-fluoro-1-nitrobenzene
  • SMILES [O-][N+](=O)c1ccc(F)cc1OC(F)F

Synthesis

  • Route1
    • null|null
      1514-87-0
    • In-stock
      5-Fluoro-2-nitrophenol|CS-W008895
      446-36-6
    • ~76%
    • In-stock
      4-Fluoro-2-difluoromethoxynitrobenzene|CS-W000041
      1214329-62-0

    References

    • EXELIXIS, INC.; Daiichi Sankyo Company, Limited; NUSS, John; WILLIAMS, Matthew; MOHAN, Raju; MARTIN, Richard; WANG, Tie-lin; TSURUOKA, Hiroyuki; AOKI, Kazumasa; HONZUMI, Masatoshi; ASOH, Yusuke; SAITO, Keiji; HOMMA, Tsuyoshi Patent: WO2010/42626 A1, 2010 ; Location in patent: Page/Page column 38-39 ; WO 2010/042626 A1
  • Route2

    References

    • SANOFI Patent: US2012/277220 A1, 2012 ; Location in patent: Page/Page column 21-22 ;
  • Route3
    • null|null
      1493-03-4
    • In-stock
      5-Fluoro-2-nitrophenol|CS-W008895
      446-36-6
    • ~%
    • In-stock
      4-Fluoro-2-difluoromethoxynitrobenzene|CS-W000041
      1214329-62-0

    References

    • Park, Chi Hoon; Choe, Hyeonjeong; Jang, In-Young; Kwon, So Yeong; Latif, Muhammad; Lee, Heung Kyoung; Lee, Hyeon Ji; Yang, Eun Hye; Yun, Jeong In; Chae, Chong Hak; Cho, Sung Yun; Choi, Sang Un; Ha, Jae Du; Jung, Heejung; Kim, Hyoung Rae; Kim, Pilho; Lee, Chong Ock; Yun, Chang-Soo; Lee, Kwangho Bioorganic and Medicinal Chemistry Letters, 2013 , vol. 23, # 22 p. 6192 - 6196

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H320-H335
Precautionary Statements : P264-P270-P330

Quality Control

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Computational Chemistry Data

  • TPSA   52.37
  • LogP   2.3353
  • H_Acceptors   3
  • H_Donors   0
  • Rotatable_Bonds   3

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