(R)-1-(6-Methoxypyridin-2-yl)ethanamine

Name: (R)-1-(6-Methoxypyridin-2-yl)ethanamine
Brand: ChemScene
Availability: InStock
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CAS No. 1212888-81-7
Cat. No. CS-0438061
Purity≥97%
MDL No.None

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Accessible (Haz class 3, 4, 5 or 8), Domestic	$158.00+
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(R)-1-(6-Methoxypyridin-2-yl)ethanamine|CS-0438061

Structure of 1212888-81-7

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Description

(R)-1-(6-Methoxypyridin-2-yl)ethanamine features a chiral ethylamine side chain attached to a 6-methoxypyridine scaffold, delivering a sterically defined, bench-stable platform for asymmetric synthesis. The para-methoxy group enhances electron density at the pyridine ring, enabling tailored interactions in catalytic and medicinal chemistry applications.

Application

(R)-1-(6-Methoxypyridin-2-yl)ethanamine serves as a valuable chiral building block in medicinal chemistry, enabling the synthesis of pyridine-containing bioactive molecules. Its well-defined stereochemistry and bench-stable nature facilitate straightforward incorporation into target scaffolds via standard amine coupling, reductive amination, or electrophilic substitution reactions. The 6-methoxy group enhances solubility and provides a handle for further derivatization, making this compound a practical choice for API development and library synthesis.

General Information

CAS No. 1212888-81-7
Cat. No. CS-0438061
Purity ≥97%
MDL No. None
Storage 4°C, protect from light
Shipping Room temperature in continental US; may vary elsewhere.
Molecular Formula C₈H₁₂N₂O
Molecular Weight 152.19
Synonym(s) (R)-1-(6-methoxypyridin-2-yl)ethan-1-amine
SMILES C[C@H](C1=CC=CC(OC)=N1)N

Computational Chemistry Data

TPSA 48.14
LogP 1.1099
H_Acceptors 3
H_Donors 1
Rotatable_Bonds 2

Safety Information

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GHS Pictogram :	GHS No : GHS06
Signal Word : Danger	UN#: 2810
Class : 6.1	Packing Group : Ⅲ
Hazard Statements : H301
Precautionary Statements : P264-P270-P330-P501

Quality Control

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Other Classifications

Building Blocks Skeleton Aromatic heterocycle compounds Pyridine compounds

Building Blocks Skeleton Chiral compounds Chiral Building Blocks

Key Words

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(R)-1-(6-Methoxypyridin-2-yl)ethanamine

CAS No. 1212888-81-7

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