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Structure of 1212021-11-8
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This boronate ester integrates a chloro substituent and nitrile group, enabling sequential functionalization via palladium-catalyzed cross-coupling. The tetramethyl-1,3,2-dioxaborolane moiety ensures high stability and reactivity under standard conditions.
3-Chloro-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzonitrile serves as a versatile Suzuki-Miyaura coupling partner, enabling efficient C–C bond formation under mild conditions. The boronate ester group offers excellent stability, ease of handling, and compatibility with diverse functional groups, while the ortho-chloro and nitrile substituents provide orthogonal reactivity for sequential transformations. This compound functions as a key building block in the synthesis of biaryl scaffolds relevant to pharmaceutical and agrochemical research.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: