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CS-W001157 4
Total: USD 88.00

5-fluoro-6-methoxy-1H-indole

  • CAS No. 1211595-72-0

  • Cat. No. CS-0036584
  • Molecule weight165.16
  • Purity≥98%
  • MDL No.None

*For research and further manufacturing use only, not for direct human use.

5-fluoro-6-methoxy-1H-indole|CS-0036584

Structure of 1211595-72-0

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General Information

  • CAS No. 1211595-72-0
  • Cat. No. CS-0036584
  • Purity ≥98%
  • MDL No. None
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₉H₈FNO
  • Molecular Weight 165.16
  • Synonym(s) 5-Fluoro-6-methoxyindole
  • SMILES COC1=C(C=C2C=CNC2=C1)F

Description

5-Fluoro-6-methoxy-1H-indole features a strategically positioned fluoro and methoxy group on the indole scaffold, enhancing electronic modulation and metabolic stability. This substitution pattern improves solubility and facilitates integration into bioactive molecules for medicinal chemistry applications.

Application

5-Fluoro-6-methoxy-1H-indole serves as a valuable building block for the synthesis of functionalized heterocycles and bioactive molecules. Its electron-withdrawing fluorine and electron-donating methoxy substituents enable predictable regioselective electrophilic substitutions and facilitate coupling reactions in medicinal chemistry workflows. The compound exhibits good bench stability and is compatible with standard purification techniques, making it suitable for scalable synthesis applications.

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

  • TPSA   25.02
  • LogP   2.3156
  • H_Acceptors   1
  • H_Donors   1
  • Rotatable_Bonds   1

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