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Structure of 1211542-12-9
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5-Fluoro-6-methylpyridin-3-amine features a strategically positioned fluorine atom and methyl group on the pyridine core, enabling enhanced metabolic stability and tunable electronic properties. This electron-deficient heterocycle integrates readily into pharmaceutical scaffolds, serving as a key building block for kinase inhibitors and bioactive molecules in medicinal chemistry.
5-Fluoro-6-methylpyridin-3-amine serves as a versatile building block in medicinal chemistry, enabling direct incorporation of fluorinated, methylated pyridine motifs into bioactive molecules. Its reactivity profile supports facile coupling reactions, including Suzuki-Miyaura and Buchwald-Hartwig amination, due to the orthogonal functionality of the amine and electron-deficient fluorine. The compound exhibits good bench stability and facilitates efficient purification, making it well-suited for scalable synthesis of kinase inhibitors and other targeted therapeutics.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: