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CS-W001157 4
Total: USD 88.00

5-Ethynylpyridine-3-carboxylic acid

  • CAS No. 1211533-87-7

  • Cat. No. CS-0158568
  • Purity≥96%
  • MDL No.MFCD18207405
  • HazMat Fee +

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    The shipment is processed through FedEx Ground under the Limited Quantity option.

    Each bottle is packed as an Excepted Quantity, with a maximum of 1g for items in class 6.1 packing group I or II, and up to 25g for all other hazardous materials.

    If shipping is charged to your FedEx account, the HazMat fee will be billed directly by the courier. Otherwise, the fee will be included on your invoice. To help you avoid the HazMat fee, we can package a 5g order of a class 6.1 packing group I or II material as five separate 1g units, and a 100g order of any other dangerous good as four 25g units. This packaging adjustment will be made unless you instruct otherwise on your purchase order. Below, you will find the fee schedule from FedEx for handling hazardous materials.

    Type
    HazMat Fee
    Excepted Quantity $0.00
    FedEx Limited Quantities Ground $0.00
    Hazmat Ground shipping $50.00+
    Inaccessible (Haz class 6.1 or 9), Domestic $68.00+
    Accessible (Haz class 3, 4, 5 or 8), Domestic $158.00+
    Inaccessible (Haz class 6.1 or 9), International $108.00+
    Accessible (Haz class 3, 4, 5 or 8), International $238.00+

    An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it.

    There is a HazMat shipping fee for each item that qualifies as a dangerous good. Please contact our quotation team via email to confirm the details.

*For research and further manufacturing use only, not for direct human use.

5-Ethynylpyridine-3-carboxylic acid|CS-0158568

Structure of 1211533-87-7

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Description

5-Ethynylpyridine-3-carboxylic acid features a conjugated alkyne moiety flanked by a pyridine ring and a carboxylic acid group, enabling efficient copper-catalyzed click chemistry. This bifunctional scaffold integrates seamlessly into bioconjugation workflows, offering high reactivity under mild conditions with excellent stability in aqueous environments.

Application

5-Ethynylpyridine-3-carboxylic acid serves as a versatile building block for the synthesis of functionalized heterocycles and conjugated systems. The terminal alkyne group enables efficient copper-catalyzed azide-alkyne cycloaddition (CuAAC), while the carboxylic acid facilitates direct amidation or esterification. Its stability under standard bench conditions and compatibility with diverse reaction environments make it ideal for modular assembly of bioactive scaffolds and materials precursors.

General Information

  • CAS No. 1211533-87-7
  • Cat. No. CS-0158568
  • Purity ≥96%
  • MDL No. MFCD18207405
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₈H₅NO₂
  • Molecular Weight 147.13
  • Synonym(s) 5-ethynylnicotinic acid
  • SMILES C#CC1=CC(=CN=C1)C(=O)O

Computational Chemistry Data

  • TPSA   50.19
  • LogP   0.7611
  • H_Acceptors   2
  • H_Donors   1
  • Rotatable_Bonds   1

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501

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