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Structure of 1211515-87-5
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2-Bromo-5-(trifluoromethyl)pyridin-3-amine features a bromine atom at the 2-position and a trifluoromethyl group at the 5-position on a pyridine ring bearing a primary amine at the 3-position. This electron-deficient heterocycle integrates readily into cross-coupling reactions, enabling efficient access to functionalized pharmaceutical intermediates under standard conditions.
2-Bromo-5-(trifluoromethyl)pyridin-3-amine serves as a versatile building block in medicinal chemistry, enabling palladium-catalyzed cross-coupling reactions due to its reactive bromide and amine functionalities. The trifluoromethyl group enhances metabolic stability and lipophilicity, while the pyridine scaffold provides favorable pharmacokinetic properties. This compound exhibits good bench stability and compatibility with standard coupling protocols, facilitating efficient synthesis of complex heterocyclic scaffolds relevant to pharmaceutical development.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: