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CS-W001157 4
Total: USD 88.00

4-Acetamidobenzene-1-sulfonyl chloride

  • CAS No. 121-60-8

  • Cat. No. CS-W012923
  • Purity≥98%
  • MDL No.MFCD00007442

*For research and further manufacturing use only, not for direct human use.

4-Acetamidobenzene-1-sulfonyl chloride|CS-W012923

Structure of 121-60-8

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General Information

  • CAS No. 121-60-8
  • Cat. No. CS-W012923
  • Purity ≥98%
  • MDL No. MFCD00007442
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₈H₈ClNO₃S
  • Molecular Weight 233.67
  • Synonym(s) N-Acetylsulfanilyl chloride
  • SMILES O=S(C1=CC=C(NC(C)=O)C=C1)(Cl)=O

Description

L-hydroxyproline has been derivatized with N-acetylsulfanilyl chloride and 5-chlorovaleric acid during the synthesis of the haptens HP1 and HP2.N-Acetylsulfanilyl chloride is used in the synthesis of N1,N1-dimethylsulfanilamide as the internal standard in the reaction. The reaction is used to determine tramadol and its O-desmethylated metabolite in blood plasma.

Synthesis

  • Route1
    • null|null
      103-84-4
    • ~95%
    • In-stock
      4-Acetamidobenzene-1-sulfonyl chloride|CS-W012923
      121-60-8

    References

    • Ludwig, Miroslav; Stverka, Pavel Collection of Czechoslovak Chemical Communications, 1996 , vol. 61, # 8 p. 1205 - 1214
  • Route2
    • 4-Acetamidobenzenesulfonic acid Sulfadimethoxine Impurity|CS-0532068
      121-62-0
    • ~88%
    • In-stock
      4-Acetamidobenzene-1-sulfonyl chloride|CS-W012923
      121-60-8

    References

    • Tan, Shiyu; Yang, Yang; Luo, Ziping; Zhao, Shuo; Huang, Dafu; Zhang, Jun; Dong, Lichun; Wang, Gang Chemical Papers, 2011 , vol. 65, # 4 p. 510 - 518
  • Route3
    • null|null
      7790-94-5
    • null|null
      103-84-4
    • ~86%
    • In-stock
      4-Acetamidobenzene-1-sulfonyl chloride|CS-W012923
      121-60-8

    References

    • Barbosa, Maria Leticia De Castro; Lima, Lidia Moreira; Tesch, Roberta; Sant'Anna, Carlos Mauricio R.; Totzke, Frank; Kubbutat, Michael H.G.; Schaechtele, Christoph; Laufer, Stefan A.; Barreiro, Eliezer J. European Journal of Medicinal Chemistry, 2014 , vol. 71, p. 1 - 14

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS05,GHS07
Signal Word : Danger
UN#: 3261
Class : 8
Packing Group : Ⅱ
Hazard Statements : H314-H335
Precautionary Statements : P260-P261-P264-P271-P280-P301+P330+P331-P304+P340-P363-P405-P501

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Computational Chemistry Data

  • TPSA   63.24
  • LogP   1.5725
  • H_Acceptors   3
  • H_Donors   1
  • Rotatable_Bonds   2

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