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Cat. No. Size / Unit Price Qty
CS-W001157 4
Total: USD 88.00

1-BOC-3,3-difluoro-4-hydroxypiperidine

  • CAS No. 1209780-71-1

  • Cat. No. CS-WAA0035
  • Purity≥95%
  • MDL No.MFCD16250751

*For research and further manufacturing use only, not for direct human use.

1-BOC-3,3-difluoro-4-hydroxypiperidine|CS-WAA0035

Structure of 1209780-71-1

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General Information

  • CAS No. 1209780-71-1
  • Cat. No. CS-WAA0035
  • Purity ≥95%
  • MDL No. MFCD16250751
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₀H₁₇F₂NO₃
  • Molecular Weight 237.24
  • Synonym(s) tert-Butyl 3,3-difluoro-4-hydroxypiperidine-1-carboxylate
  • SMILES O=C(N1CCC(C(C1)(F)F)O)OC(C)(C)C

Synthesis

  • Route1
    • In-stock
      Di-tert-butyl dicarbonate|CS-0017817
      24424-99-5
    • 3,3-Difluoropiperidin-4-ol|CS-0051629
      1239596-54-3
    • ~%
    • In-stock
      1-BOC-3,3-difluoro-4-hydroxypiperidine|CS-WAA0035
      1209780-71-1

    References

    • ACTELION PHARMACEUTICALS LTD; CORMINBOEUF, Olivier; POZZI, Davide Patent: WO2013/171694 A1, 2013 ; Location in patent: Page/Page column 30 ;
  • Route2

    References

    • ACTELION PHARMACEUTICALS LTD; CORMINBOEUF, Olivier; POZZI, Davide Patent: WO2013/171694 A1, 2013 ;
  • Route3
    • 1-Benzyl-3,3-difluoropiperidin-4-ol|CS-W001352
      1239596-53-2
    • ~%
    • In-stock
      1-BOC-3,3-difluoro-4-hydroxypiperidine|CS-WAA0035
      1209780-71-1

    References

    • ACTELION PHARMACEUTICALS LTD; CORMINBOEUF, Olivier; POZZI, Davide Patent: WO2013/171694 A1, 2013 ;

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   49.77
  • LogP   1.6234
  • H_Acceptors   3
  • H_Donors   1
  • Rotatable_Bonds   0

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