4-Bromo-N-methyl-2-pyrimidinamine

Name: 4-Bromo-N-methyl-2-pyrimidinamine
Brand: ChemScene
Availability: InStock
Rating: 5 (1 reviews)

CAS No. 1209458-16-1
Cat. No. CS-W009033
Purity≥98%
MDL No.MFCD13193672

HazMat Fee +

HazMat Fee

An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it. There is a HazMat shipping fee for each item that qualifies as a dangerous good, except in the following scenarios:

The shipment is processed through FedEx Ground under the Limited Quantity option.

Each bottle is packed as an Excepted Quantity, with a maximum of 1g for items in class 6.1 packing group I or II, and up to 25g for all other hazardous materials.

If shipping is charged to your FedEx account, the HazMat fee will be billed directly by the courier. Otherwise, the fee will be included on your invoice. To help you avoid the HazMat fee, we can package a 5g order of a class 6.1 packing group I or II material as five separate 1g units, and a 100g order of any other dangerous good as four 25g units. This packaging adjustment will be made unless you instruct otherwise on your purchase order. Below, you will find the fee schedule from FedEx for handling hazardous materials.

Type	HazMat Fee
Excepted Quantity	$0.00
FedEx Limited Quantities Ground	$0.00
Hazmat Ground shipping	$50.00+
Inaccessible (Haz class 6.1 or 9), Domestic	$68.00+
Accessible (Haz class 3, 4, 5 or 8), Domestic	$158.00+
Inaccessible (Haz class 6.1 or 9), International	$108.00+
Accessible (Haz class 3, 4, 5 or 8), International	$238.00+

An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it.

There is a HazMat shipping fee for each item that qualifies as a dangerous good. Please contact our quotation team via email to confirm the details.

*For research and further manufacturing use only, not for direct human use.

4-Bromo-N-methyl-2-pyrimidinamine|CS-W009033

Structure of 1209458-16-1

Size

Price

Quantity

* Please select Quantity before adding items.

General Information

CAS No. 1209458-16-1
Cat. No. CS-W009033
Purity ≥98%
MDL No. MFCD13193672
Storage 4°C, protect from light
Shipping Room temperature in continental US; may vary elsewhere.
Molecular Formula C₅H₆BrN₃
Molecular Weight 188.03
Synonym(s) 4-Bromo-N-methylpyrimidin-2-amine
SMILES CNC1=NC=CC(Br)=N1

Description

4-Bromo-N-methyl-2-pyrimidinamine features a bromine substituent at the 4-position and a methylamino group at nitrogen-2, creating a versatile scaffold for medicinal chemistry. The electron-deficient pyrimidine core enables efficient coupling reactions, while the N-methyl group enhances metabolic stability and membrane permeability. This compound serves as a key intermediate in the synthesis of kinase inhibitors and antiviral agents.

Application

4-Bromo-N-methyl-2-pyrimidinamine serves as a versatile building block in medicinal chemistry, enabling palladium-catalyzed cross-coupling reactions due to its reactive bromine and amine functionalities. The N-methyl group enhances metabolic stability while maintaining compatibility with standard coupling protocols. Its pyrimidine core provides a scaffold for constructing bioactive heterocycles, offering bench-stable, easily purified reagents ideal for iterative synthesis workflows in API development.

Safety Information

Download SDS

GHS Pictogram :	GHS No : GHS07
Signal Word : Warning	UN#: N/A
Class : N/A	Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

To search for quality control of cas , please enter both the product number and the lot/batch number.

Computational Chemistry Data

TPSA 37.81
LogP 1.2808
H_Acceptors 3
H_Donors 1
Rotatable_Bonds 1

Other Classifications

Building Blocks Functional Group Bromide

Building Blocks Skeleton Aromatic heterocycle compounds Pyrimidine compounds

Key Words

4-Bromo-N-methyl-2-pyrimidinamine sigma4-Bromo-N-methyl-2-pyrimidinamine manufacturer4-Bromo-N-methyl-2-pyrimidinamine price4-Bromo-N-methyl-2-pyrimidinamine structure4-Bromo-N-methyl-2-pyrimidinamine SDSbuy 4-Bromo-N-methyl-2-pyrimidinamine4-Bromo-N-methyl-2-pyrimidinamine supplier4-Bromo-N-methyl-2-pyrimidinamine uses4-Bromo-N-methyl-2-pyrimidinamine molecular weightprice of 4-Bromo-N-methyl-2-pyrimidinamine4-Bromo-N-methyl-2-pyrimidinamine chemical name formula of 4-Bromo-N-methyl-2-pyrimidinamine

Salutation:	*Country or Region:
*Applicant Name:	*Organization Name:
*Email Address:	Quantity:
CAS NO. :	Product Name:
Remarks:
Upload Pictures

CAS.No.		Product Name
Applicant Name *		Email Address *
Phone Number *		Organization Name*
Country or Region*		Quantity*
Remarks:

Product Name:
Cat. No.: .		CAS NO. :
Quantity:

4-Bromo-N-methyl-2-pyrimidinamine

CAS No. 1209458-16-1

Recommended Products