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Structure of 1208170-17-5
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4-Chloro-6-methyl-2-(methylthio)pyrimidine-5-carbonitrile features a trifunctional pyrimidine core with chlorine, methylthio, and nitrile groups positioned for orthogonal reactivity. This electron-deficient scaffold enables direct incorporation into heterocyclic scaffolds via cross-coupling or nucleophilic displacement, offering a robust platform for medicinal chemistry campaigns requiring precise structural tuning and metabolic stability.
4-Chloro-6-methyl-2-(methylthio)pyrimidine-5-carbonitrile serves as a versatile building block in medicinal chemistry, enabling efficient construction of pyrimidine-based scaffolds. Its regioselective reactivity at the C4-chloro site facilitates palladium-catalyzed cross-coupling reactions, while the nitrile and methylthio groups offer orthogonal functionalization potential. The compound exhibits excellent bench stability and clean purification profiles, making it well-suited for scalable synthesis and API intermediate development.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501
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Lot numbers can be found on the outside label of a product: