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Structure of 1208084-77-8
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8-Bromo-[1,2,4]triazolo[4,3-c]pyrimidine is a heterocyclic building block featuring a bromine substituent at the 8-position, enabling direct functionalization in cross-coupling reactions. The fused triazolopyrimidine core offers enhanced stability and favorable electronic properties for applications in medicinal chemistry and materials science.
8-Bromo-[1,2,4]triazolo[4,3-c]pyrimidine serves as a versatile heterocyclic building block in medicinal chemistry, enabling efficient construction of purine-like scaffolds. Its bromine substituent facilitates palladium-catalyzed cross-coupling reactions, including Suzuki and Buchwald–Hartwig aminations, with high functional group tolerance. The triazolopyrimidine core exhibits robust bench stability and simplifies purification, making it ideal for iterative synthesis workflows in API development and target-oriented compound libraries.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H320
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Precautionary Statements : P264-P270-P280-P302+P352-P330-P362-P501
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Lot numbers can be found on the outside label of a product: