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CS-W001157 4
Total: USD 88.00

6-Bromopyrazolo[1,5-a]pyridin-4-ol

  • CAS No. 1207840-22-9

  • Cat. No. CS-0138353
  • Purity≥97%
  • MDL No.MFCD27959322

*For research and further manufacturing use only, not for direct human use.

6-Bromopyrazolo[1,5-a]pyridin-4-ol|CS-0138353

Structure of 1207840-22-9

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General Information

  • CAS No. 1207840-22-9
  • Cat. No. CS-0138353
  • Purity ≥97%
  • MDL No. MFCD27959322
  • Storage 4°C, stored under nitrogen
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₇H₅BrN₂O
  • Molecular Weight 213.03
  • Synonym(s) None
  • SMILES OC1=CC(Br)=CN2C1=CC=N2

Description

6-Bromopyrazolo[1,5-a]pyridin-4-ol features a brominated pyrazolopyridinol core with a strategically positioned hydroxyl group. This electron-deficient heterocycle serves as a robust scaffold for cross-coupling reactions and integrates readily into bioactive molecules. The compound exhibits bench-stable handling and compatibility with palladium-catalyzed transformations under standard conditions.

Application

6-Bromopyrazolo[1,5-a]pyridin-4-ol serves as a versatile building block for heterocyclic synthesis, enabling palladium-catalyzed cross-coupling reactions due to its stable bromine functionality. The phenolic hydroxyl group provides additional handle for derivatization or metal complexation. Its bench-stable solid form facilitates handling and purification, making it well-suited for iterative synthesis in medicinal chemistry and process development workflows.

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501

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Computational Chemistry Data

  • TPSA   37.53
  • LogP   1.8024
  • H_Acceptors   3
  • H_Donors   1
  • Rotatable_Bonds   0

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