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5-Ethylpyridin-3-amine

  • CAS No. 1207529-93-8

  • Cat. No. CS-0198881
  • Molecule weight122.17
  • Purity≥97%
  • MDL No.None

*For research and further manufacturing use only, not for direct human use.

5-Ethylpyridin-3-amine|CS-0198881

Structure of 1207529-93-8

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General Information

  • CAS No. 1207529-93-8
  • Cat. No. CS-0198881
  • Purity ≥97%
  • MDL No. None
  • Storage 4°C, protect from light
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₇H₁₀N₂
  • Molecular Weight 122.17
  • Synonym(s) 5-Ethyl-3-pyridinamine
  • SMILES NC1=CC(CC)=CN=C1

Description

5-Ethylpyridin-3-amine features a pyridine core functionalized with an ethyl group at the 5-position and a primary amine at the 3-position, enabling versatile coordination in catalytic systems. The electron-donating ethyl substituent enhances nucleophilicity, while the amine moiety facilitates conjugation and metal chelation. This combination supports robust reactivity in transition metal-catalyzed transformations and synthetic applications requiring tunable basicity and solubility.

Application

5-Ethylpyridin-3-amine serves as a versatile building block in medicinal chemistry, enabling the construction of bioactive heterocycles through standard coupling and functionalization reactions. Its pyridine core provides enhanced solubility and metabolic stability, while the ortho-amino and ethyl substituents offer complementary sites for derivatization. The compound exhibits excellent bench stability and facilitates straightforward purification, making it well-suited for iterative synthesis workflows in API development.

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P280-P302+P352

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Computational Chemistry Data

  • TPSA   38.91
  • LogP   1.2262
  • H_Acceptors   2
  • H_Donors   1
  • Rotatable_Bonds   1

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