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CS-W001157 4
Total: USD 88.00

6-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)quinolin-2(1H)-one

  • CAS No. 1207370-28-2

  • Cat. No. CS-0041255
  • Molecule weight271.12
  • Purity≥96%
  • MDL No.MFCD25542188

*For research and further manufacturing use only, not for direct human use.

6-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)quinolin-2(1H)-one|CS-0041255

Structure of 1207370-28-2

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General Information

  • CAS No. 1207370-28-2
  • Cat. No. CS-0041255
  • Purity ≥96%
  • MDL No. MFCD25542188
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₅H₁₈BNO₃
  • Molecular Weight 271.12
  • Synonym(s) None
  • SMILES O=C1NC2=C(C=C(B3OC(C)(C)C(C)(C)O3)C=C2)C=C1

Description

6-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)quinolin-2(1H)-one integrates a boronate ester handle at the 6-position of a quinolin-2(1H)-one scaffold, enabling efficient Suzuki-Miyaura coupling. This bench-stable reagent combines enhanced solubility with predictable reactivity, streamlining access to functionalized quinoline derivatives in medicinal chemistry and materials synthesis.

Application

6-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)quinolin-2(1H)-one serves as a versatile boronate building block for palladium-catalyzed cross-coupling reactions. The quinolin-2(1H)-one core provides a stable, functionalized heterocyclic scaffold with demonstrated utility in medicinal chemistry and materials science. Bench-stable and readily purified, it facilitates efficient late-stage diversification via Suzuki-Miyaura coupling, enabling rapid access to complex molecular architectures.

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   51.32
  • LogP   1.8273
  • H_Acceptors   3
  • H_Donors   1
  • Rotatable_Bonds   1

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