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CS-W001157 4
Total: USD 88.00

2-Bromo-6-chlorothiazolo[4,5-c]pyridine

  • CAS No. 1206250-70-5

  • Cat. No. CS-0513722
  • Purity≥95%
  • MDL No.MFCD14581886

*For research and further manufacturing use only, not for direct human use.

2-Bromo-6-chlorothiazolo[4,5-c]pyridine|CS-0513722

Structure of 1206250-70-5

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General Information

  • CAS No. 1206250-70-5
  • Cat. No. CS-0513722
  • Purity ≥95%
  • MDL No. MFCD14581886
  • Storage 4°C, stored under nitrogen
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₆H₂BrClN₂S
  • Molecular Weight 249.52
  • Synonym(s) None
  • SMILES ClC1=CC(SC(Br)=N2)=C2C=N1

Description

2-Bromo-6-chlorothiazolo[4,5-c]pyridine features a fused thiazolopyridine core with orthogonal halogen substituents enabling selective cross-coupling. This electron-deficient heterocycle integrates readily into advanced pharmaceutical scaffolds and serves as a key intermediate in medicinal chemistry campaigns requiring halogen-directed functionalization.

Application

2-Bromo-6-chlorothiazolo[4,5-c]pyridine serves as a versatile heterocyclic building block for the synthesis of pharmaceutical intermediates and functional materials. Its complementary halogenation pattern enables selective cross-coupling reactions, including Suzuki and Buchwald–Hartwig transformations, with high chemoselectivity and excellent functional group tolerance. The molecule exhibits robust bench stability and facilitates efficient purification, making it well-suited for iterative synthetic sequences in medicinal chemistry and process development.

Safety Information

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Computational Chemistry Data

  • TPSA   25.78
  • LogP   3.1072
  • H_Acceptors   3
  • H_Donors   0
  • Rotatable_Bonds   0

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