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CS-W001157 4
Total: USD 88.00

N6-Cyclopropyl-9H-purine-2,6-diamine

  • CAS No. 120503-69-7

  • Cat. No. CS-0187573
  • Purity≥95%
  • MDL No.MFCD12215664

*For research and further manufacturing use only, not for direct human use.

N6-Cyclopropyl-9H-purine-2,6-diamine|CS-0187573

Structure of 120503-69-7

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General Information

  • CAS No. 120503-69-7
  • Cat. No. CS-0187573
  • Purity ≥95%
  • MDL No. MFCD12215664
  • Storage 4°C, protect from light
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₈H₁₀N₆
  • Molecular Weight 190.21
  • Synonym(s) None
  • SMILES N1=CNC2=C1N=C(N=C2NC3CC3)N

Description

Pharmaceutical secondary standards for application in quality control, provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards.Choline chloride may be used as a pharmaceutical reference standard for the determination of the analyte in pharmaceutical formulations by liquid chromatography technique.

Application

N6-Cyclopropyl-9H-purine-2,6-diamine serves as a versatile purine scaffold for medicinal chemistry applications, enabling the synthesis of kinase inhibitors and nucleoside analogs. Its cyclopropyl substitution at the N6 position enhances metabolic stability and modulates hydrogen bonding capacity, while the diamine functionality supports facile derivatization via coupling reactions. Bench-stable and readily purified by chromatography, it functions as a key building block in the construction of biologically active heterocycles.

Synthesis

  • Route1
    • 2-Amino-6-chloropurine Clofarabine Impurity|CS-0229147
      10310-21-1
    • null|null
      765-30-0
    • ~85%
    • In-stock
      N6-Cyclopropyl-9H-purine-2,6-diamine|CS-0187573
      120503-69-7

    References

    • Holy, Antonin; Votruba, Ivan; Tloustova, Eva; Masojidkova, Milena Collection of Czechoslovak Chemical Communications, 2001 , vol. 66, # 10 p. 1545 - 1592

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   92.51
  • LogP   0.5094
  • H_Acceptors   5
  • H_Donors   3
  • Rotatable_Bonds   2

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