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CS-W001157 4
Total: USD 88.00

4-Bromo-6-methylisoquinoline

  • CAS No. 1204298-52-1

  • Cat. No. CS-0044900
  • Molecule weight222.08
  • Purity≥98%
  • MDL No.MFCD12922845

*For research and further manufacturing use only, not for direct human use.

4-Bromo-6-methylisoquinoline|CS-0044900

Structure of 1204298-52-1

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General Information

  • CAS No. 1204298-52-1
  • Cat. No. CS-0044900
  • Purity ≥98%
  • MDL No. MFCD12922845
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₀H₈BrN
  • Molecular Weight 222.08
  • Synonym(s) 4-Bromo-6-methyl-2-azanaphthalene
  • SMILES CC1=CC2=C(C=NC=C2Br)C=C1

Description

4-Bromo-6-methylisoquinoline delivers a sterically accessible isoquinoline core with complementary halogen and methyl handles. This bench-stable scaffold integrates readily into cross-coupling workflows, enabling rapid access to functionalized heterocycles for medicinal chemistry and materials applications.

Application

4-Bromo-6-methylisoquinoline serves as a versatile building block in medicinal chemistry, enabling palladium-catalyzed cross-coupling reactions for the construction of complex isoquinoline-based scaffolds. Its bromine handle facilitates reliable C–C bond formation under standard Suzuki, Stille, or Negishi conditions, while the methyl group enhances electronic and steric control. The compound exhibits good bench stability and is compatible with a range of functional groups, making it ideal for iterative synthesis of bioactive heterocycles.

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   12.89
  • LogP   3.30572
  • H_Acceptors   1
  • H_Donors   0
  • Rotatable_Bonds   0

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