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CS-W001157 4
Total: USD 88.00

(2-Aminopyridin-3-yl)boronic acid

  • CAS No. 1204112-62-8

  • Cat. No. CS-0174006
  • Purity≥97%
  • MDL No.MFCD11865292

*For research and further manufacturing use only, not for direct human use.

(2-Aminopyridin-3-yl)boronic acid|CS-0174006

Structure of 1204112-62-8

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General Information

  • CAS No. 1204112-62-8
  • Cat. No. CS-0174006
  • Purity ≥97%
  • MDL No. MFCD11865292
  • Storage -20°C, protect from light
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₅H₇BN₂O₂
  • Molecular Weight 137.93
  • Synonym(s) 2-Aminopyridine-3-boronic acid·2HCl2
  • SMILES NC1=C(B(O)O)C=CC=N1

Description

This boronate moiety integrates seamlessly into Suzuki-Miyaura cross-coupling reactions, offering enhanced reactivity and stability under standard conditions. The ortho-aminopyridyl group enables efficient coordination in catalytic systems, facilitating selective functionalization of heteroaromatic scaffolds with minimal side-product formation.

Application

(2-Aminopyridin-3-yl)boronic acid serves as a versatile building block in transition-metal-catalyzed cross-coupling reactions, enabling efficient C–C bond formation under mild conditions. Its ortho-amino functionality enhances coordination to palladium catalysts and improves reaction efficiency in Suzuki-Miyaura coupling. The boronic acid moiety offers excellent bench stability, facile purification, and compatibility with diverse functional groups, making it ideal for constructing biologically relevant heterocyclic scaffolds in medicinal chemistry and materials science applications.

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   79.37
  • LogP   -1.6564
  • H_Acceptors   4
  • H_Donors   3
  • Rotatable_Bonds   1

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