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Structure of 1202897-48-0
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5-Fluoro-2-iodobenzoic acid methyl ester features a strategically positioned fluorine atom and iodine substituent on the aromatic ring, enabling selective cross-coupling reactions. The methyl ester group enhances solubility and reactivity in transition metal-catalyzed transformations. This compound serves as a key intermediate for synthesizing bioactive molecules in medicinal chemistry and materials science.
5-Fluoro-2-iodobenzoic acid methyl ester serves as a versatile building block for palladium-catalyzed cross-coupling reactions, enabling efficient construction of biaryl and heteroaryl scaffolds. The iodine moiety facilitates reliable Suzuki, Stille, and Negishi couplings, while the fluorinated benzene core enhances metabolic stability in downstream applications. Bench-stable and readily purified by flash chromatography, it functions effectively in medicinal chemistry and materials synthesis workflows.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: