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Structure of 1202577-61-4
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trans-(4-(Trifluoromethyl)cyclohexyl)methanol features a rigid, bench-stable cyclohexane scaffold with a para-trifluoromethyl substituent and a primary alcohol group. This configuration enables selective functionalization in synthetic workflows, particularly in medicinal chemistry applications requiring enhanced metabolic stability and lipophilicity.
trans-(4-(Trifluoromethyl)cyclohexyl)methanol serves as a versatile building block for medicinal chemistry and agrochemical synthesis, offering a stable, bench-ready cyclohexane scaffold with orthogonal functional handles. Its trifluoromethyl group enhances metabolic stability and lipophilicity, while the primary alcohol enables straightforward derivatization via esterification, ether formation, or oxidation to aldehyde/carboxylic acid. The trans-configuration provides defined stereochemistry critical for structure-activity studies, and the compound exhibits excellent handling properties and purification compatibility in standard synthetic workflows.
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: