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CS-W001157 4
Total: USD 88.00

4-((2-Hydroxyethyl)(methyl)amino)benzaldehyde

  • CAS No. 1201-91-8

  • Cat. No. CS-0134780
  • Purity≥97%
  • MDL No.MFCD00963547

*For research and further manufacturing use only, not for direct human use.

4-((2-Hydroxyethyl)(methyl)amino)benzaldehyde|CS-0134780

Structure of 1201-91-8

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General Information

  • CAS No. 1201-91-8
  • Cat. No. CS-0134780
  • Purity ≥97%
  • MDL No. MFCD00963547
  • Storage 4°C, stored under nitrogen
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₀H₁₃NO₂
  • Molecular Weight 179.22
  • Synonym(s) N-methyl-N-hydroxyethyl-4-amino benzaldehyde
  • SMILES O=CC1=CC=C(N(C)CCO)C=C1

Application

4-((2-Hydroxyethyl)(methyl)amino)benzaldehyde serves as a versatile building block in medicinal chemistry, enabling the synthesis of bioactive heterocycles and functionalized aromatic scaffolds. Its aldehyde group facilitates imine formation and reductive amination, while the pendant hydroxyl and tertiary amine enable hydrogen bonding and solubility enhancement. The molecule exhibits bench stability and compatibility with standard purification methods, facilitating its use in multi-step syntheses and library generation.

Synthesis

  • Route1

    References

    • Lupo, Donald; Ringsdorf, Helmut; Schuster, Andreas; Seitz, Markus Journal of the American Chemical Society, 1994 , vol. 116, # 23 p. 10498 - 10506
  • Route2

    References

    • BECTON, DICKINSON AND COMPANY Patent: WO2006/25887 A2, 2006 ; Location in patent: Page/Page column 21; 44-45 ;
  • Route3

    References

    • DE711665 , ; DRP/DRBP Org.Chem. US2141090 , ;

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H315-H319-H335
Precautionary Statements : P261-P264-P271-P280-P302+P352-P304+P340-P362-P405-P501

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Computational Chemistry Data

  • TPSA   40.54
  • LogP   0.9276
  • H_Acceptors   3
  • H_Donors   1
  • Rotatable_Bonds   4

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