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Structure of 1198339-37-5
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This chiral azetidine carboxylic acid features a sterically hindered tert-butyl ester protecting group, enabling stable handling and selective deprotection under mild conditions. The (2R)-configured scaffold integrates readily into peptide macrocyclization strategies, offering enhanced conformational rigidity for drug discovery applications.
(2R)-1-[(tert-Butoxy)carbonyl]-2-methylazetidine-2-carboxylic acid serves as a stereochemically defined building block for the synthesis of bioactive azetidine-containing scaffolds. Its tert-butyl ester group enables straightforward protection and subsequent deprotection under mild acidic conditions, while the constrained azetidine ring imparts conformational rigidity beneficial in medicinal chemistry. The molecule exhibits good bench stability and facilitates efficient coupling reactions with amines and alcohols, supporting its use in modular peptide-like and heterocyclic library construction.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501
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Lot numbers can be found on the outside label of a product: