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methyl 5-amino-4-(4-amino-1-oxoisoindolin-2-yl)-5-oxopentanoate Lenalidomide Impurity

  • CAS No. 1198299-53-4

  • Cat. No. CS-0163849
  • Purity≥98%
  • MDL No.None

*For research and further manufacturing use only, not for direct human use.

methyl 5-amino-4-(4-amino-1-oxoisoindolin-2-yl)-5-oxopentanoate  Lenalidomide Impurity|CS-0163849

Structure of 1198299-53-4

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General Information

  • CAS No. 1198299-53-4
  • Cat. No. CS-0163849
  • Purity ≥98%
  • MDL No. None
  • Storage Sealed in dry,2-8℃
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₄H₁₇N₃O₄
  • Molecular Weight 291.30
  • Synonym(s) methyl 5-amino-4-(4-amino-1-oxoisoindolin-2-yl)-5-oxopentanoate
  • SMILES O=C(OC)CCC(N(CC1=C2C=CC=C1N)C2=O)C(N)=O

Synthesis

  • Route1
    • dimethyl 2-(4-amino-1-oxoisoindolin-2-yl)pentanedioate  Lenalidomide Impurity|CS-0163848
      1198299-50-1
    • ~75%
    • methyl 5-amino-4-(4-amino-1-oxoisoindolin-2-yl)-5-oxopentanoate  Lenalidomide Impurity|CS-0163849
      1198299-53-4

    References

    • NANJING CAVENDISH BIO-ENGINEERING TECHNOLOGY CO., LTD.; YAN, Rong; YANG, Hao; XU, Yongxiang Patent:   WO2010/139266 A1, 2010 ; Location in patent: Page/Page column 43-44 ;

Safety Information

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GHS Pictogram : N/A
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UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : N/A
Precautionary Statements : N/A

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Computational Chemistry Data

  • TPSA   115.72
  • LogP   0.0317
  • H_Acceptors   5
  • H_Donors   2
  • Rotatable_Bonds   5

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