Tel:

Email:

EN
Cat. No. Size / Unit Price Qty
CS-W001157 4
Total: USD 88.00

p-Hydroxymandelic acid

  • CAS No. 1198-84-1

  • Cat. No. CS-0059383
  • Purity≥95%
  • MDL No.MFCD00004234

*For research and further manufacturing use only, not for direct human use.

p-Hydroxymandelic acid|CS-0059383

Structure of 1198-84-1

Please choose your location and provide accurate information for you
Size Stock
Price Quantity

* Please select Quantity before adding items.

General Information

  • CAS No. 1198-84-1
  • Cat. No. CS-0059383
  • Purity ≥95%
  • MDL No. MFCD00004234
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₈H₈O₄
  • Molecular Weight None
  • Synonym(s) None
  • SMILES OC(C(O)C1=CC=C(C=C1)O)=O

Description

p-Hydroxymandelic acid features a phenolic hydroxyl group para to the mandelic acid backbone, enhancing solubility and enabling selective derivatization. This configuration supports efficient conjugation in bioconjugation workflows and facilitates integration into functionalized molecular scaffolds under standard conditions.

Application

p-Hydroxymandelic acid serves as a versatile building block in medicinal chemistry, featuring a benzylic hydroxyl group and a carboxylic acid that enable straightforward derivatization. Its phenolic hydroxyl allows for selective protection and conjugation, while the α-hydroxy acid moiety supports stereoselective transformations and incorporation into chiral scaffolds. The compound exhibits good bench stability and is amenable to standard purification techniques, facilitating integration into multi-step synthesis workflows.

Synthesis

  • Route1
    • Glyoxalic acid 50%w/w in water|CS-W019807
      298-12-4
    • null|null
      108-95-2
    • ~90%
    • In-stock
      p-Hydroxymandelic acid|CS-0059383
      1198-84-1

    References

    • Varala, Ravi; Kotra, Vijay; Alam, M. Mujahid; Kumar, N. Ramesh; Ganapaty; Adapa, Srinivas R. Indian Journal of Chemistry - Section B Organic and Medicinal Chemistry, 2008 , vol. 47, # 8 p. 1243 - 1248
  • Route2
    • N-(4-Hydroxyphenyl)glycine|CS-0201679
      122-87-2
    • p-Hydroxybenzaldehyde Bisoprolol Impurity|CS-0229513
      123-08-0
    • ~%
    • In-stock
      p-Hydroxymandelic acid|CS-0059383
      1198-84-1

    References

    • US2003/144558 A1, ;
  • Route3
    • null|null
      67-66-3
    • p-Hydroxybenzaldehyde Bisoprolol Impurity|CS-0229513
      123-08-0
    • ~77%
    • In-stock
      p-Hydroxymandelic acid|CS-0059383
      1198-84-1

    References

    • Yang, Ben-Yong; Yang, De-Hong Journal of Chemical Research, 2011 , vol. 35, # 8 p. 484 - 485

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

To search for quality control of cas , please enter both the product number and the lot/batch number.

Computational Chemistry Data

  • TPSA   77.76
  • LogP   0.5102
  • H_Acceptors   3
  • H_Donors   3
  • Rotatable_Bonds   2

Other Classifications

Recently Viewed Products

Leave US a Message
Upload Pictures

Key Words

  • p-Hydroxymandelic acid sigmap-Hydroxymandelic acid manufacturerp-Hydroxymandelic acid pricep-Hydroxymandelic acid structurep-Hydroxymandelic acid SDSbuy p-Hydroxymandelic acidp-Hydroxymandelic acid supplierp-Hydroxymandelic acid usesp-Hydroxymandelic acid molecular weightprice of p-Hydroxymandelic acidp-Hydroxymandelic acid chemical name formula of p-Hydroxymandelic acid
This product is not sold in the region.
Confirm
How to get a Lot Number

Lot numbers can be found on the outside label of a product:

ChemScene Label