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Structure of 119647-73-3
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Ethyl 7-oxo-4,5,6,7-tetrahydro-1H-indole-2-carboxylate is a bench-stable heterocyclic intermediate featuring a fused indoline core with a ketone at C7 and an ester functionality at C2. This scaffold integrates readily into medicinal chemistry campaigns targeting CNS-active compounds and kinase inhibitors, offering high compatibility in Pd-catalyzed cross-coupling reactions due to its electron-deficient aromatic system and stable functional group tolerance.
Ethyl 7-oxo-4,5,6,7-tetrahydro-1H-indole-2-carboxylate serves as a versatile building block in synthetic organic chemistry, enabling access to indole-based scaffolds through standard functional group manipulations. The ketone and ester functionalities offer orthogonal reactivity for selective transformations, including nucleophilic additions and coupling reactions. Its bench-stable nature and compatibility with common reaction conditions facilitate efficient synthesis of heterocyclic intermediates and API precursors in medicinal chemistry workflows.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: