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CS-W001157 4
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tert-Butyl (6-formylpyridin-3-yl)carbamate

  • CAS No. 1196156-55-4

  • Cat. No. CS-0654612
  • Purity≥98%
  • MDL No.None

*For research and further manufacturing use only, not for direct human use.

tert-Butyl (6-formylpyridin-3-yl)carbamate|CS-0654612

Structure of 1196156-55-4

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General Information

  • CAS No. 1196156-55-4
  • Cat. No. CS-0654612
  • Purity ≥98%
  • MDL No. None
  • Storage 4°C, stored under nitrogen
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₁H₁₄N₂O₃
  • Molecular Weight 222.24
  • Synonym(s) None
  • SMILES CC(C)(C)OC(=O)NC1=CN=C(C=C1)C=O

Description

tert-Butyl (6-formylpyridin-3-yl)carbamate features a pyridine scaffold with a formyl group at the 6-position and a carbamate-protected amine at the 3-position. This bifunctional building block enables direct incorporation into diverse synthetic scaffolds, offering compatibility with reductive amination and nucleophilic addition reactions under standard conditions.

Application

tert-Butyl (6-formylpyridin-3-yl)carbamate serves as a versatile building block for heterocyclic synthesis, enabling direct functionalization at the pyridine C6 position. The formyl group facilitates efficient reductive amination, Ugi-type coupling, and oxime formation, while the tert-butoxycarbonyl (Boc) group provides stable protection of the amine under acidic and basic conditions. Its bench stability and compatibility with standard purification protocols make it well-suited for iterative synthetic sequences in medicinal chemistry and API development.

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501

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Computational Chemistry Data

  • TPSA   68.29
  • LogP   2.2411
  • H_Acceptors   4
  • H_Donors   1
  • Rotatable_Bonds   2

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