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Structure of 1196152-08-5
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4-Ethynylpyridin-2(1H)-one features a reactive alkyne group conjugated to a pyridinone scaffold, enabling efficient copper-catalyzed azide-alkyne cycloaddition (CuAAC) for bioconjugation and molecular diversification. The electron-deficient pyridinone ring enhances regioselectivity in click reactions while maintaining stability under standard conditions.
4-Ethynylpyridin-2(1H)-one serves as a versatile building block in medicinal chemistry, enabling efficient access to functionalized heterocycles via copper-catalyzed azide-alkyne cycloaddition (CuAAC). Its pyridinone core provides enhanced solubility and hydrogen-bonding capacity, while the terminal alkyne facilitates conjugation with diverse azide-containing moieties. The compound exhibits excellent bench stability and compatibility with standard synthetic protocols, simplifying purification and integration into multi-step syntheses.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: