Tel:

Email:

EN
Cat. No. Size / Unit Price Qty
CS-W001157 4
Total: USD 88.00

2-Chloro-6-methylbenzaldehyde

  • CAS No. 1194-64-5

  • Cat. No. CS-0043396
  • Purity≥97%
  • MDL No.MFCD01934409

*For research and further manufacturing use only, not for direct human use.

2-Chloro-6-methylbenzaldehyde|CS-0043396

Structure of 1194-64-5

Please choose your location and provide accurate information for you
Size Stock
Price Quantity

* Please select Quantity before adding items.

General Information

  • CAS No. 1194-64-5
  • Cat. No. CS-0043396
  • Purity ≥97%
  • MDL No. MFCD01934409
  • Storage 4°C, stored under nitrogen
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₈H₇ClO
  • Molecular Weight 154.59
  • Synonym(s) 3-Chloro-2-formyltoluene
  • SMILES O=CC1=C(C)C=CC=C1Cl

Description

2-Chloro-6-methylbenzaldehyde features a chlorinated aromatic ring with a methyl group at the para position relative to the aldehyde. This electron-deficient benzaldehyde integrates readily into Suzuki and Ullmann coupling reactions, offering enhanced reactivity under standard conditions. The ortho-chloro substituent imparts steric and electronic control, enabling selective functionalization in complex synthesis.

Application

2-Chloro-6-methylbenzaldehyde serves as a versatile building block in medicinal chemistry and agrochemical synthesis, enabling direct functionalization at the aromatic ring due to its ortho-chloro and methyl substituents. The aldehyde group facilitates efficient imine formation, reductive amination, and coupling reactions, while the chloro and methyl groups offer predictable electronic and steric modulation. Its bench-stable nature and compatibility with standard synthetic protocols make it ideal for multi-step synthesis and process development.

Synthesis

  • Route1

    References

    • ATHEROGENICS, INC. Patent: WO2006/4903 A2, 2006 ; Location in patent: Page/Page column 124-125 ;
  • Route2
    • null|null
      32347-02-7
    • null|null
      917-54-4
    • ~%
    • In-stock
      2-Chloro-6-methylbenzaldehyde|CS-0043396
      1194-64-5

    References

    • EP1602645 A1, ; Page/Page column 14 ; EP 1602645 A1
  • Route3

    References

    • Achar, Tapas Kumar; Maiti, Saikat; Mal, Prasenjit RSC Advances, 2014 , vol. 4, # 25 p. 12834 - 12839

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H315-H319-H335
Precautionary Statements : P261-P264-P271-P280-P302+P352-P304+P340-P362+P364-P405-P501

Quality Control

To search for quality control of cas , please enter both the product number and the lot/batch number.

Computational Chemistry Data

  • TPSA   17.07
  • LogP   2.46092
  • H_Acceptors   1
  • H_Donors   0
  • Rotatable_Bonds   1

Other Classifications

Recently Viewed Products

Leave US a Message
Upload Pictures

Key Words

  • 2-Chloro-6-methylbenzaldehyde sigma2-Chloro-6-methylbenzaldehyde manufacturer2-Chloro-6-methylbenzaldehyde price2-Chloro-6-methylbenzaldehyde structure2-Chloro-6-methylbenzaldehyde SDSbuy 2-Chloro-6-methylbenzaldehyde2-Chloro-6-methylbenzaldehyde supplier2-Chloro-6-methylbenzaldehyde uses2-Chloro-6-methylbenzaldehyde molecular weightprice of 2-Chloro-6-methylbenzaldehyde2-Chloro-6-methylbenzaldehyde chemical name formula of 2-Chloro-6-methylbenzaldehyde
This product is not sold in the region.
Confirm
How to get a Lot Number

Lot numbers can be found on the outside label of a product:

ChemScene Label