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Structure of 1193387-31-3
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6-Fluoro-1H-1,3-benzodiazole-4-carboxylic acid features a fluorinated benzodiazole core with a carboxylic acid group at the 4-position, enabling direct incorporation into bioactive molecules. The electron-withdrawing fluorine substituent enhances metabolic stability and modulates electronic properties. This scaffold delivers improved membrane permeability and target engagement in medicinal chemistry applications.
6-Fluoro-1H-1,3-benzodiazole-4-carboxylic acid serves as a versatile building block for the synthesis of bioactive heterocycles and pharmaceutical intermediates. Its well-defined electronic profile and compatibility with standard coupling reactions enable efficient derivatization at the carboxylic acid moiety. The molecule exhibits bench stability and facilitates access to diverse scaffolds through amide formation, esterification, and Suzuki-type cross-coupling protocols, making it a practical choice for medicinal chemistry campaigns and process development.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501
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Lot numbers can be found on the outside label of a product: