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Structure of 1193244-89-1
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This boronate moiety features a sterically hindered tertiary alcohol flanked by an electron-deficient pyrimidine ring, enabling robust coupling in cross-coupling protocols. The 5-bromopyrimidin-2-yl group provides a high-affinity handle for palladium-mediated transformations under standard conditions.
2-(5-Bromopyrimidin-2-yl)propan-2-ol serves as a versatile building block in medicinal chemistry, enabling efficient construction of pyrimidine-based scaffolds. Its bromine substituent facilitates palladium-catalyzed cross-coupling reactions, while the tertiary alcohol group offers stability and ease of purification. The molecule demonstrates excellent functional group tolerance and bench stability, making it well-suited for iterative synthesis workflows in API development.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501
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Lot numbers can be found on the outside label of a product: