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CS-W001157 4
Total: USD 88.00

2-(Pyridin-2-yl)-4,5-dihydrooxazole

  • CAS No. 119165-69-4

  • Cat. No. CS-0094593
  • Purity≥97%
  • MDL No.None

*For research and further manufacturing use only, not for direct human use.

2-(Pyridin-2-yl)-4,5-dihydrooxazole|CS-0094593

Structure of 119165-69-4

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General Information

  • CAS No. 119165-69-4
  • Cat. No. CS-0094593
  • Purity ≥97%
  • MDL No. None
  • Storage -20°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₈H₈N₂O
  • Molecular Weight 148.16
  • Synonym(s) Pyridine, 2-(4,5-dihydro-2-oxazolyl)- (9CI)
  • SMILES C1(C2=NCCO2)=NC=CC=C1

Description

2-(Pyridin-2-yl)-4,5-dihydrooxazole features a fused heterocyclic core integrating a pyridine ring with a dihydrooxazole moiety, offering enhanced stability and tunable reactivity. This scaffold serves as a key building block in medicinal chemistry, enabling efficient coupling in transition-metal-catalyzed transformations. The compound exhibits favorable solubility in organic solvents and compatibility with standard synthetic protocols.

Application

2-(Pyridin-2-yl)-4,5-dihydrooxazole serves as a versatile heterocyclic building block in medicinal chemistry, enabling the construction of pyridine-fused oxazolines through standard functional group manipulations. Its stability under ambient conditions and compatibility with common coupling reactions facilitate efficient integration into complex molecular architectures. The dihydrooxazole core exhibits predictable reactivity in hydrogenation and electrophilic substitution processes, supporting scalable synthesis workflows.

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501

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Computational Chemistry Data

  • TPSA   34.48
  • LogP   0.8584
  • H_Acceptors   3
  • H_Donors   0
  • Rotatable_Bonds   1

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