(2,4-Difluoro-3-(methoxycarbonyl)phenyl)boronic acid

Name: (2,4-Difluoro-3-(methoxycarbonyl)phenyl)boronic acid
Brand: ChemScene
Availability: InStock
Rating: 5 (1 reviews)

CAS No. 1190989-12-8
Cat. No. CS-0176096
Purity≥98%
MDL No.None

HazMat Fee +

HazMat Fee

An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it. There is a HazMat shipping fee for each item that qualifies as a dangerous good, except in the following scenarios:

The shipment is processed through FedEx Ground under the Limited Quantity option.

Each bottle is packed as an Excepted Quantity, with a maximum of 1g for items in class 6.1 packing group I or II, and up to 25g for all other hazardous materials.

If shipping is charged to your FedEx account, the HazMat fee will be billed directly by the courier. Otherwise, the fee will be included on your invoice. To help you avoid the HazMat fee, we can package a 5g order of a class 6.1 packing group I or II material as five separate 1g units, and a 100g order of any other dangerous good as four 25g units. This packaging adjustment will be made unless you instruct otherwise on your purchase order. Below, you will find the fee schedule from FedEx for handling hazardous materials.

Type	HazMat Fee
Excepted Quantity	$0.00
FedEx Limited Quantities Ground	$0.00
Hazmat Ground shipping	$50.00+
Inaccessible (Haz class 6.1 or 9), Domestic	$68.00+
Accessible (Haz class 3, 4, 5 or 8), Domestic	$158.00+
Inaccessible (Haz class 6.1 or 9), International	$108.00+
Accessible (Haz class 3, 4, 5 or 8), International	$238.00+

An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it.

There is a HazMat shipping fee for each item that qualifies as a dangerous good. Please contact our quotation team via email to confirm the details.

*For research and further manufacturing use only, not for direct human use.

(2,4-Difluoro-3-(methoxycarbonyl)phenyl)boronic acid|CS-0176096

Structure of 1190989-12-8

Size

Price

Quantity

* Please select Quantity before adding items.

General Information

CAS No. 1190989-12-8
Cat. No. CS-0176096
Purity ≥98%
MDL No. None
Storage Store at room temperature
Shipping Room temperature in continental US; may vary elsewhere.
Molecular Formula C₈H₇BF₂O₄
Molecular Weight 215.95
Synonym(s) Methyl 3-borono-2,6-difluorobenzoate
SMILES COC(C1=C(F)C=CC(B(O)O)=C1F)=O

Description

This boronic acid features a methoxycarbonyl group flanked by fluorine substituents, enhancing electronic modulation and stability. The ortho-fluorines facilitate oxidative stability and improve coupling efficiency in Suzuki-Miyaura reactions. This bench-stable reagent integrates readily into complex molecular architectures, enabling precise C–C bond formation under mild conditions.

Application

(2,4-Difluoro-3-(methoxycarbonyl)phenyl)boronic acid serves as a versatile building block in Suzuki-Miyaura cross-coupling reactions, enabling efficient construction of biaryl scaffolds with enhanced metabolic stability. Its fluorinated aryl core and ester-functionalized side chain provide excellent bench stability, predictable reactivity, and compatibility with diverse reaction conditions. The molecule facilitates the synthesis of complex heterocycles and pharmaceutically relevant frameworks, offering high functional group tolerance and straightforward purification via standard chromatographic methods.

Safety Information

Download SDS

GHS Pictogram :	GHS No : GHS07
Signal Word : Warning	UN#: N/A
Class : N/A	Packing Group : N/A
Hazard Statements : H315-H319-H335
Precautionary Statements : P261-P264-P271-P280-P302+P352-P304+P340-P362+P364-P405-P501

Quality Control

To search for quality control of cas , please enter both the product number and the lot/batch number.

Computational Chemistry Data

TPSA 66.76
LogP -0.5688
H_Acceptors 4
H_Donors 2
Rotatable_Bonds 2

Other Classifications

Building Blocks Functional Group Boronic Acid And Its Ester

Building Blocks Functional Group Ester

Building Blocks Skeleton Aromatic ring compounds Benzene compounds

Key Words

1190989-12-8 sigma1190989-12-8 manufacturer1190989-12-8 price1190989-12-8 structure1190989-12-8 SDSbuy 1190989-12-81190989-12-8 supplier1190989-12-8 uses1190989-12-8 molecular weightprice of 1190989-12-81190989-12-8 chemical name formula of 1190989-12-8

Salutation:	*Country or Region:
*Applicant Name:	*Organization Name:
*Email Address:	Quantity:
CAS NO. :	Product Name:
Remarks:
Upload Pictures

CAS.No.		Product Name
Applicant Name *		Email Address *
Phone Number *		Organization Name*
Country or Region*		Quantity*
Remarks:

Product Name:
Cat. No.: .		CAS NO. :
Quantity:

(2,4-Difluoro-3-(methoxycarbonyl)phenyl)boronic acid

CAS No. 1190989-12-8

Recommended Products