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CS-W001157 4
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1H-Pyrrolo[3,2-b]pyridine-7-carboxylic acid

  • CAS No. 1190319-18-6

  • Cat. No. CS-W007232
  • Purity≥98%
  • MDL No.MFCD12963157

*For research and further manufacturing use only, not for direct human use.

1H-Pyrrolo[3,2-b]pyridine-7-carboxylic acid|CS-W007232

Structure of 1190319-18-6

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General Information

  • CAS No. 1190319-18-6
  • Cat. No. CS-W007232
  • Purity ≥98%
  • MDL No. MFCD12963157
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₈H₆N₂O₂
  • Molecular Weight 162.15
  • Synonym(s) 4-Azaindole-7-carboxylic acid
  • SMILES O=C(C1=C(NC=C2)C2=NC=C1)O

Description

1H-Pyrrolo[3,2-b]pyridine-7-carboxylic acid features a fused heterocyclic core with a carboxylic acid handle at the 7-position, enabling direct conjugation or derivatization. The electron-deficient pyrrolopyridine scaffold enhances reactivity in transition metal-catalyzed couplings and supports integration into bioactive molecules. This bench-stable, moisture-tolerant building block facilitates rapid access to functionalized scaffolds for medicinal chemistry and materials science applications.

Application

1H-Pyrrolo[3,2-b]pyridine-7-carboxylic acid serves as a versatile building block for heterocyclic scaffolds in medicinal chemistry. Its carboxylic acid functionality enables direct amidation, esterification, and coupling reactions, facilitating the synthesis of target molecules for drug discovery. The fused bicyclic core exhibits favorable stability and solubility profiles, supporting efficient purification and scalability in synthetic workflows.

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

  • TPSA   65.98
  • LogP   1.2611
  • H_Acceptors   2
  • H_Donors   2
  • Rotatable_Bonds   1

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