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CS-W001157 4
Total: USD 88.00

5-Bromo-3-chloropicolinic acid

  • CAS No. 1189513-51-6

  • Cat. No. CS-W003837
  • Purity≥96%
  • MDL No.MFCD12827552
  • HazMat Fee +

    HazMat Fee

    An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it. There is a HazMat shipping fee for each item that qualifies as a dangerous good, except in the following scenarios:

    The shipment is processed through FedEx Ground under the Limited Quantity option.

    Each bottle is packed as an Excepted Quantity, with a maximum of 1g for items in class 6.1 packing group I or II, and up to 25g for all other hazardous materials.

    If shipping is charged to your FedEx account, the HazMat fee will be billed directly by the courier. Otherwise, the fee will be included on your invoice. To help you avoid the HazMat fee, we can package a 5g order of a class 6.1 packing group I or II material as five separate 1g units, and a 100g order of any other dangerous good as four 25g units. This packaging adjustment will be made unless you instruct otherwise on your purchase order. Below, you will find the fee schedule from FedEx for handling hazardous materials.

    Type
    HazMat Fee
    Excepted Quantity $0.00
    FedEx Limited Quantities Ground $0.00
    Hazmat Ground shipping $50.00+
    Inaccessible (Haz class 6.1 or 9), Domestic $68.00+
    Accessible (Haz class 3, 4, 5 or 8), Domestic $158.00+
    Inaccessible (Haz class 6.1 or 9), International $108.00+
    Accessible (Haz class 3, 4, 5 or 8), International $238.00+

    An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it.

    There is a HazMat shipping fee for each item that qualifies as a dangerous good. Please contact our quotation team via email to confirm the details.

*For research and further manufacturing use only, not for direct human use.

5-Bromo-3-chloropicolinic acid|CS-W003837

Structure of 1189513-51-6

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Description

5-Bromo-3-chloropicolinic acid is a halogenated picolinic acid derivative featuring bromine at the 5-position and chlorine at the 3-position of the pyridine ring. This electron-deficient heterocycle integrates readily into cross-coupling reactions, offering enhanced reactivity and stability under standard conditions. The dual halogen substitution enables selective functionalization in synthetic sequences.

Application

5-Bromo-3-chloropicolinic acid serves as a versatile building block for the synthesis of bioactive heterocycles and pharmaceutical intermediates. Its dual halogenation pattern enables reliable cross-coupling reactions, including Suzuki and Stille couplings, while the carboxylic acid group facilitates direct derivatization or salt formation. The compound exhibits excellent bench stability and is compatible with standard purification techniques, making it well-suited for scalable medicinal chemistry campaigns.

General Information

  • CAS No. 1189513-51-6
  • Cat. No. CS-W003837
  • Purity ≥96%
  • MDL No. MFCD12827552
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₆H₃BrClNO₂
  • Molecular Weight 236.45
  • Synonym(s) 5-Bromo-3-chloropyridine-2-carboxylic acid
  • SMILES Brc1cnc(c(c1)Cl)C(=O)O

Computational Chemistry Data

  • TPSA   50.19
  • LogP   2.1957
  • H_Acceptors   2
  • H_Donors   1
  • Rotatable_Bonds   1

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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