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CS-W001157 4
Total: USD 88.00

5-Bromo-3-chloropicolinic acid

  • CAS No. 1189513-51-6

  • Cat. No. CS-W003837
  • Purity≥96%
  • MDL No.MFCD12827552

*For research and further manufacturing use only, not for direct human use.

5-Bromo-3-chloropicolinic acid|CS-W003837

Structure of 1189513-51-6

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General Information

  • CAS No. 1189513-51-6
  • Cat. No. CS-W003837
  • Purity ≥96%
  • MDL No. MFCD12827552
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₆H₃BrClNO₂
  • Molecular Weight 236.45
  • Synonym(s) 5-Bromo-3-chloropyridine-2-carboxylic acid
  • SMILES Brc1cnc(c(c1)Cl)C(=O)O

Description

5-Bromo-3-chloropicolinic acid is a halogenated picolinic acid derivative featuring bromine at the 5-position and chlorine at the 3-position of the pyridine ring. This electron-deficient heterocycle integrates readily into cross-coupling reactions, offering enhanced reactivity and stability under standard conditions. The dual halogen substitution enables selective functionalization in synthetic sequences.

Application

5-Bromo-3-chloropicolinic acid serves as a versatile building block for the synthesis of bioactive heterocycles and pharmaceutical intermediates. Its dual halogenation pattern enables reliable cross-coupling reactions, including Suzuki and Stille couplings, while the carboxylic acid group facilitates direct derivatization or salt formation. The compound exhibits excellent bench stability and is compatible with standard purification techniques, making it well-suited for scalable medicinal chemistry campaigns.

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

  • TPSA   50.19
  • LogP   2.1957
  • H_Acceptors   2
  • H_Donors   1
  • Rotatable_Bonds   1

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