3-Methyl-1H-pyrazolo[3,4-b]pyridin-5-amine

Name: 3-Methyl-1H-pyrazolo[3,4-b]pyridin-5-amine
Brand: ChemScene
Availability: InStock
Rating: 5 (1 reviews)

CAS No. 1186608-73-0
Cat. No. CS-0051272
Purity≥95%
MDL No.MFCD13193614

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Type	HazMat Fee
Excepted Quantity	$0.00
FedEx Limited Quantities Ground	$0.00
Hazmat Ground shipping	$50.00+
Inaccessible (Haz class 6.1 or 9), Domestic	$68.00+
Accessible (Haz class 3, 4, 5 or 8), Domestic	$158.00+
Inaccessible (Haz class 6.1 or 9), International	$108.00+
Accessible (Haz class 3, 4, 5 or 8), International	$238.00+

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3-Methyl-1H-pyrazolo[3,4-b]pyridin-5-amine|CS-0051272

Structure of 1186608-73-0

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Description

3-Methyl-1H-pyrazolo[3,4-b]pyridin-5-amine features a fused heterocyclic core with a pendant amine and methyl group, offering enhanced electron density at the pyridine nitrogen. This scaffold enables direct incorporation into kinase inhibitors and bioactive small molecules, serving as a robust platform for medicinal chemistry optimization under standard bench conditions.

Application

3-Methyl-1H-pyrazolo[3,4-b]pyridin-5-amine serves as a versatile heterocyclic building block in medicinal chemistry, enabling efficient access to kinase inhibitor scaffolds and other bioactive architectures. Its electron-rich pyrazolopyridine core exhibits robust bench stability, facilitates straightforward functionalization at the 5-amino and 3-methyl positions, and demonstrates compatibility with standard coupling reactions, protecting group strategies, and late-stage diversification protocols common in API development.

General Information

CAS No. 1186608-73-0
Cat. No. CS-0051272
Purity ≥95%
MDL No. MFCD13193614
Storage Store at room temperature
Shipping Room temperature in continental US; may vary elsewhere.
Molecular Formula C₇H₈N₄
Molecular Weight None
Synonym(s) 3-Methyl-1H-pyrazolo[3,4-b]pyridine-5-amine
SMILES CC1=NNC2=C1C=C(N)C=N2

Computational Chemistry Data

TPSA 67.59
LogP 0.84852
H_Acceptors 3
H_Donors 2
Rotatable_Bonds 0

Safety Information

Download SDS

GHS Pictogram :	GHS No : GHS07
Signal Word : Warning	UN#: N/A
Class : N/A	Packing Group : N/A
Hazard Statements : H315-H319
Precautionary Statements : P264-P280-P302+P352-P305+P351+P338-P332+P313-P337+P313-P362+P364

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Other Classifications

Building Blocks Skeleton Aromatic heterocycle compounds Pyridine compounds

Building Blocks Skeleton Aromatic heterocycle compounds Pyrazole compounds

Biochemistry Biochemicals and Reagents Nucleosides, Nucleotides, Oligonucleotides Nucleobases and their Analogs

Key Words

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3-Methyl-1H-pyrazolo[3,4-b]pyridin-5-amine

CAS No. 1186608-73-0

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