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CS-W001157 4
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tert-Butyl (2-(2-(methylamino)ethoxy)ethyl)carbamate

  • CAS No. 1185772-28-4

  • Cat. No. CS-0133667
  • Purity≥95%
  • MDL No.MFCD25368799

*For research and further manufacturing use only, not for direct human use.

tert-Butyl (2-(2-(methylamino)ethoxy)ethyl)carbamate|CS-0133667

Structure of 1185772-28-4

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General Information

  • CAS No. 1185772-28-4
  • Cat. No. CS-0133667
  • Purity ≥95%
  • MDL No. MFCD25368799
  • Storage 4°C, protect from light
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₀H₂₂N₂O₃
  • Molecular Weight 218.30
  • Synonym(s) None
  • SMILES O=C(OC(C)(C)C)NCCOCCNC

Description

tert-Butyl (2-(2-(methylamino)ethoxy)ethyl)carbamate features a bifunctional ether-amine scaffold that enables seamless incorporation into peptide extensions and bioconjugation workflows. The tert-butyl carbamate group provides stable protection under standard conditions, while the pendant methylaminoethoxy moiety offers enhanced solubility and nucleophilicity for downstream derivatization.

Application

tert-Butyl (2-(2-(methylamino)ethoxy)ethyl)carbamate serves as a stable, bench-ready protecting group for primary amines, enabling selective functionalization in complex molecule synthesis. It facilitates efficient deprotection under mild acidic conditions and exhibits excellent compatibility with diverse reaction types, including coupling and cyclization protocols. Its orthogonal behavior to other common protecting groups supports streamlined synthetic sequences in medicinal chemistry and API development workflows.

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS05,GHS07
Signal Word : Danger
UN#: 2735
Class : 8
Packing Group : Ⅲ
Hazard Statements : H315-H318-H335
Precautionary Statements : P261-P264-P271-P280-P302+P352-P304+P340-P362+P364-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   59.59
  • LogP   0.7471
  • H_Acceptors   4
  • H_Donors   2
  • Rotatable_Bonds   6

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