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Structure of 1185767-06-9
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5-Bromo-6-fluoro-1-methyl-1H-indazole features a sterically unhindered indazole core with complementary halogen substituents enabling direct functionalization. The methyl group at the nitrogen enhances solubility and metabolic stability, while the ortho-bromine and fluoro positions facilitate cross-coupling reactions under standard conditions. This compound serves as a key building block in medicinal chemistry for targeted drug discovery.
5-Bromo-6-fluoro-1-methyl-1H-indazole serves as a versatile building block in medicinal chemistry, enabling palladium-catalyzed cross-coupling reactions due to its orthogonal halogen reactivity. The bromo and fluoro substituents facilitate sequential functionalization, while the methyl group enhances metabolic stability. Its bench-stable solid form and compatibility with standard reaction conditions make it well-suited for iterative synthesis of complex heterocyclic scaffolds.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501
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Lot numbers can be found on the outside label of a product: