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(5-Methyl-1,2,4-oxadiazol-3-yl)methanamine;hydrochloride

  • CAS No. 1184986-84-2

  • Cat. No. CS-0036626
  • Molecule weightNone
  • Purity≥95%
  • MDL No.MFCD11506367

*For research and further manufacturing use only, not for direct human use.

(5-Methyl-1,2,4-oxadiazol-3-yl)methanamine;hydrochloride|CS-0036626

Structure of 1184986-84-2

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General Information

  • CAS No. 1184986-84-2
  • Cat. No. CS-0036626
  • Purity ≥95%
  • MDL No. MFCD11506367
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₄H₈ClN₃O
  • Molecular Weight None
  • Synonym(s) C-(5-Methyl-[1,2,4]oxadiazol-3-yl)-methylamine hydrochloride
  • SMILES CC1=NC(CN)=NO1.Cl

Description

This bench-stable oxadiazole derivative features a methyl-substituted 1,2,4-oxadiazole ring linked to a primary amine group, delivering enhanced solubility and reactivity in synthetic transformations. The hydrochloride salt form ensures improved handling and storage stability, enabling efficient incorporation into pharmaceutical intermediates and bioactive molecule scaffolds under standard conditions.

Application

(5-Methyl-1,2,4-oxadiazol-3-yl)methanamine;hydrochloride serves as a stable, bench-ready building block for the construction of bioactive heterocycles. The oxadiazole core provides enhanced metabolic stability and favorable physicochemical properties, while the primary amine functionality enables straightforward derivatization via acylation, alkylation, or coupling reactions. Its hydrochloride salt form ensures excellent solubility and handling characteristics, facilitating integration into standard medicinal chemistry workflows.

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302
Precautionary Statements : P264-P270-P301+P310-P330-P501

Quality Control

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Computational Chemistry Data

  • TPSA   64.94
  • LogP   0.25852
  • H_Acceptors   4
  • H_Donors   1
  • Rotatable_Bonds   1

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