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CS-W001157 4
Total: USD 88.00

2-Bromo-1-(bromomethyl)-3-fluorobenzene

  • CAS No. 1184918-22-6

  • Cat. No. CS-0695881
  • Molecule weight267.92
  • Purity≥98%
  • MDL No.None

*For research and further manufacturing use only, not for direct human use.

2-Bromo-1-(bromomethyl)-3-fluorobenzene|CS-0695881

Structure of 1184918-22-6

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General Information

  • CAS No. 1184918-22-6
  • Cat. No. CS-0695881
  • Purity ≥98%
  • MDL No. None
  • Storage 4°C, stored under nitrogen
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₇H₅Br₂F
  • Molecular Weight 267.92
  • Synonym(s) None
  • SMILES FC1=C(Br)C(CBr)=CC=C1

Description

Thalidomide-NH-PEG4-COOH is a PROTAC linker featuring a thalidomide, a hydrophilic PEG spacer, and a carboxylic acid. Thalidomide recruits E3 Ligase for the ubiquitinylation and subsequent destruction of a given protein. The carboxylic acid is reactive towards amines and alcohols with the use of coupling reagents such as EDC or HATU.

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS05,GHS07
Signal Word : Danger
UN#: 3261
Class : 8
Packing Group : Ⅱ
Hazard Statements : H302-H314
Precautionary Statements : P260-P264-P270-P280-P301+P330+P331-P304+P340-P363-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   0
  • LogP   3.4831
  • H_Acceptors   0
  • H_Donors   0
  • Rotatable_Bonds   1

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