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Structure of 1176414-91-7
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5-Bromo-1-methyl-1,2,3,4-tetrahydroisoquinoline delivers a brominated, N-methylated tetrahydroisoquinoline scaffold with enhanced electrophilic reactivity at the aromatic ring. This bench-stable compound integrates readily into transition-metal-catalyzed coupling reactions and serves as a key intermediate in the synthesis of bioactive alkaloids and pharmaceutical candidates.
5-Bromo-1-methyl-1,2,3,4-tetrahydroisoquinoline serves as a versatile building block in medicinal chemistry, enabling palladium-catalyzed cross-coupling reactions due to its well-defined aryl bromide functionality. The tetrahydroisoquinoline core provides a rigid, bioactive scaffold with favorable pharmacokinetic properties. Its methylated nitrogen enhances metabolic stability and improves solubility, while the bromine substituent allows for selective functionalization under standard coupling conditions. This compound facilitates efficient access to complex heterocyclic architectures relevant to CNS-targeted therapeutics and kinase inhibitors.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501
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Lot numbers can be found on the outside label of a product: