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CS-W001157 4
Total: USD 88.00

6-Chloro-3-pyridineethanol

  • CAS No. 117528-28-6

  • Cat. No. CS-0040781
  • Purity≥93%
  • MDL No.MFCD15526719

*For research and further manufacturing use only, not for direct human use.

6-Chloro-3-pyridineethanol|CS-0040781

Structure of 117528-28-6

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General Information

  • CAS No. 117528-28-6
  • Cat. No. CS-0040781
  • Purity ≥93%
  • MDL No. MFCD15526719
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₇H₈ClNO
  • Molecular Weight 157.60
  • Synonym(s) 2-(6-Chloropyridin-3-YL)ethanol
  • SMILES OCCC1=CC=C(Cl)N=C1

Description

6-Chloro-3-pyridineethanol features a chlorinated pyridine ring linked to an ethanolic side chain, offering enhanced reactivity and solubility in polar solvents. This configuration supports efficient coupling reactions and facilitates incorporation into bioactive scaffolds under standard conditions.

Application

6-Chloro-3-pyridineethanol serves as a versatile building block for medicinal chemistry and agrochemical synthesis, enabling efficient functionalization at the pyridine ring. Its chloro substituent facilitates palladium-catalyzed cross-coupling reactions, while the primary alcohol group allows for straightforward derivatization via esterification, etherification, or oxidation. The compound exhibits good bench stability and is compatible with common protecting group strategies, facilitating its use in multi-step syntheses of complex heterocyclic scaffolds.

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

  • TPSA   33.12
  • LogP   1.2698
  • H_Acceptors   2
  • H_Donors   1
  • Rotatable_Bonds   2

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