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CS-W001157 4
Total: USD 88.00

(S)-2-Aminooctanoic acid

  • CAS No. 116783-26-7

  • Cat. No. CS-W006364
  • Purity≥97%
  • MDL No.MFCD03701463

*For research and further manufacturing use only, not for direct human use.

(S)-2-Aminooctanoic acid|CS-W006364

Structure of 116783-26-7

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General Information

  • CAS No. 116783-26-7
  • Cat. No. CS-W006364
  • Purity ≥97%
  • MDL No. MFCD03701463
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₈H₁₇NO₂
  • Molecular Weight 159.23
  • Synonym(s) Octanoic acid,2-amino-
  • SMILES CCCCCC[C@H](N)C(O)=O

Description

(S)-2-Aminooctanoic acid is a chiral aliphatic amino acid featuring a defined stereochemistry at the alpha carbon. This configuration imparts distinct conformational properties valuable in peptide synthesis and medicinal chemistry. The molecule exhibits enhanced solubility in polar solvents and maintains stability under standard bench conditions, enabling reliable integration into complex molecular architectures without racemization.

Application

(S)-2-Aminooctanoic acid serves as a valuable chiral building block in peptide synthesis and medicinal chemistry, offering well-established stereochemical control at the alpha position. Its aliphatic side chain provides favorable solubility and stability for bench-scale applications, while the amine and carboxylic acid functionalities enable straightforward derivatization and incorporation into bioactive scaffolds.

Synthesis

  • Route1

    References

    • Angewandte Chemie - International Edition, , vol. 40, # 10 p. 1948 - 1951
  • Route2
    • null|null
      119817-31-1
    • ~%
    • In-stock
      (S)-2-Aminooctanoic acid|CS-W006364
      116783-26-7

    References

    • Organic and Biomolecular Chemistry, , vol. 2, # 24 p. 3584 - 3587
  • Route3
    • 2-Oxooctanoic acid|CS-0516450
      328-51-8
    • ~%
    • In-stock
      (R)-2-Aminooctanoic acid|CS-0152326
      106819-03-8
    • In-stock
      (S)-2-Aminooctanoic acid|CS-W006364
      116783-26-7

    References

    • Journal of the American Chemical Society, , vol. 128, # 33 p. 10923 - 10929

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   63.32
  • LogP   1.3687
  • H_Acceptors   2
  • H_Donors   2
  • Rotatable_Bonds   6

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